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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TLL2 All Species: 47.88
Human Site: S229 Identified Species: 81.03
UniProt: Q9Y6L7 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6L7 NP_036597.1 1015 113557 S229 G G G P Q A I S I G K N C D K
Chimpanzee Pan troglodytes XP_507953 1164 129143 S378 G G G P Q A I S I G K N C D K
Rhesus Macaque Macaca mulatta XP_001101883 1013 114718 S227 G N G P Q A I S I G K N C D K
Dog Lupus familis XP_543945 1032 114883 S236 G G G P Q A I S I G K N C D K
Cat Felis silvestris
Mouse Mus musculus Q9WVM6 1012 113234 S226 G G G P Q A I S I G K N C D K
Rat Rattus norvegicus XP_345032 1014 113481 S228 G G G P Q A I S I G K N C D K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509196 1014 114574 S228 G N G P Q A I S I G K N C D K
Chicken Gallus gallus Q9DER7 1008 114873 S223 G N G P Q A I S I G K N C D K
Frog Xenopus laevis O57382 1019 114873 S232 G G G P Q A I S I G K N C D K
Zebra Danio Brachydanio rerio O57460 1022 115518 S236 G N G P Q A I S I G K N C D K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25723 1067 121762 S218 G N G R Q P I S I G R N C E K
Honey Bee Apis mellifera XP_393866 1225 138704 S418 G N G P Q A I S I G K N C D K
Nematode Worm Caenorhab. elegans Q20176 951 107516 Y200 D F S S I M H Y A R D T F S R
Sea Urchin Strong. purpuratus P98069 639 71875
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.5 72.4 89.6 N.A. 90.2 89.6 N.A. 73 72.5 75 73.2 N.A. 41.5 46.2 40.6 37.8
Protein Similarity: 100 86.7 83.3 92.7 N.A. 93.8 93.9 N.A. 83.8 83 86.3 84.4 N.A. 57.4 59.8 57.6 47.9
P-Site Identity: 100 100 93.3 100 N.A. 100 100 N.A. 93.3 93.3 100 93.3 N.A. 66.6 93.3 0 0
P-Site Similarity: 100 100 93.3 100 N.A. 100 100 N.A. 93.3 93.3 100 93.3 N.A. 80 93.3 6.6 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 79 0 0 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 86 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 0 8 0 0 79 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 86 43 86 0 0 0 0 0 0 86 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 86 0 86 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 79 0 0 0 86 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 43 0 0 0 0 0 0 0 0 0 86 0 0 0 % N
% Pro: 0 0 0 79 0 8 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 86 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 8 0 0 0 0 0 8 8 0 0 0 8 % R
% Ser: 0 0 8 8 0 0 0 86 0 0 0 0 0 8 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _