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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLL2
All Species:
46.97
Human Site:
S716
Identified Species:
79.49
UniProt:
Q9Y6L7
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6L7
NP_036597.1
1015
113557
S716
N
M
R
V
E
F
K
S
D
N
T
V
S
K
R
Chimpanzee
Pan troglodytes
XP_507953
1164
129143
S865
N
M
R
V
E
F
K
S
D
N
T
V
S
K
R
Rhesus Macaque
Macaca mulatta
XP_001101883
1013
114718
S714
N
M
R
I
E
F
K
S
D
N
T
V
S
K
K
Dog
Lupus familis
XP_543945
1032
114883
S723
N
M
R
V
E
F
K
S
D
N
T
V
S
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVM6
1012
113234
S713
N
M
R
V
E
F
K
S
D
N
T
V
S
K
R
Rat
Rattus norvegicus
XP_345032
1014
113481
S715
N
M
R
V
E
F
K
S
D
N
T
V
S
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509196
1014
114574
S715
N
M
R
I
E
F
K
S
D
N
T
V
S
K
K
Chicken
Gallus gallus
Q9DER7
1008
114873
S709
N
M
R
I
E
F
R
S
D
N
T
V
S
K
K
Frog
Xenopus laevis
O57382
1019
114873
S719
T
V
R
I
E
F
K
S
D
N
T
V
S
K
K
Zebra Danio
Brachydanio rerio
O57460
1022
115518
S723
N
M
R
I
E
F
K
S
D
N
T
V
S
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25723
1067
121762
S737
I
L
R
L
E
F
Y
S
D
R
T
V
Q
R
S
Honey Bee
Apis mellifera
XP_393866
1225
138704
S914
S
M
R
V
T
F
T
S
D
N
S
I
Q
K
T
Nematode Worm
Caenorhab. elegans
Q20176
951
107516
C663
N
A
G
C
E
H
T
C
Q
N
R
L
G
S
Y
Sea Urchin
Strong. purpuratus
P98069
639
71875
G351
T
I
S
L
Q
F
T
G
F
E
L
V
G
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.5
72.4
89.6
N.A.
90.2
89.6
N.A.
73
72.5
75
73.2
N.A.
41.5
46.2
40.6
37.8
Protein Similarity:
100
86.7
83.3
92.7
N.A.
93.8
93.9
N.A.
83.8
83
86.3
84.4
N.A.
57.4
59.8
57.6
47.9
P-Site Identity:
100
100
86.6
100
N.A.
100
100
N.A.
86.6
80
73.3
86.6
N.A.
46.6
53.3
20
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
66.6
73.3
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
86
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
86
0
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
93
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
8
0
0
0
0
15
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
0
36
0
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
65
0
0
0
0
0
0
79
36
% K
% Leu:
0
8
0
15
0
0
0
0
0
0
8
8
0
0
0
% L
% Met:
0
72
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
72
0
0
0
0
0
0
0
0
86
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
8
0
0
0
15
0
0
% Q
% Arg:
0
0
86
0
0
0
8
0
0
8
8
0
0
8
36
% R
% Ser:
8
0
8
0
0
0
0
86
0
0
8
0
72
15
8
% S
% Thr:
15
0
0
0
8
0
22
0
0
0
79
0
0
0
8
% T
% Val:
0
8
0
43
0
0
0
0
0
0
0
86
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _