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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TLL2 All Species: 42.42
Human Site: S862 Identified Species: 71.79
UniProt: Q9Y6L7 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6L7 NP_036597.1 1015 113557 S862 K P D P T V A S G S S M F L R
Chimpanzee Pan troglodytes XP_507953 1164 129143 S1011 K P D P T V A S G S S M F L R
Rhesus Macaque Macaca mulatta XP_001101883 1013 114718 T860 I P D P L V A T G N K M F V R
Dog Lupus familis XP_543945 1032 114883 S869 K P D P V V A S G S S L F V R
Cat Felis silvestris
Mouse Mus musculus Q9WVM6 1012 113234 T859 K P D P V V A T G S S L F L R
Rat Rattus norvegicus XP_345032 1014 113481 T861 K P D P V V A T G S S L F L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509196 1014 114574 T861 I P D P L V A T G N K M F L R
Chicken Gallus gallus Q9DER7 1008 114873 T855 I P E P L I A T G N K M F L R
Frog Xenopus laevis O57382 1019 114873 S865 E P S P V V A S T N N M F L R
Zebra Danio Brachydanio rerio O57460 1022 115518 T869 I P E P L I S T G N K M Y L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25723 1067 121762 S883 E P Y A V I A S T N E M F M V
Honey Bee Apis mellifera XP_393866 1225 138704 T1060 E P H P I L A T G N Q M Y M V
Nematode Worm Caenorhab. elegans Q20176 951 107516 Y801 R R G F Q A H Y T S L C G G R
Sea Urchin Strong. purpuratus P98069 639 71875 P489 D G H E D T S P L I G R Y C G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.5 72.4 89.6 N.A. 90.2 89.6 N.A. 73 72.5 75 73.2 N.A. 41.5 46.2 40.6 37.8
Protein Similarity: 100 86.7 83.3 92.7 N.A. 93.8 93.9 N.A. 83.8 83 86.3 84.4 N.A. 57.4 59.8 57.6 47.9
P-Site Identity: 100 100 60 80 N.A. 80 80 N.A. 66.6 53.3 60 40 N.A. 33.3 33.3 13.3 0
P-Site Similarity: 100 100 80 93.3 N.A. 93.3 93.3 N.A. 80 80 80 80 N.A. 60 73.3 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 8 79 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % C
% Asp: 8 0 50 0 8 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 22 0 15 8 0 0 0 0 0 0 8 0 0 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 72 0 0 % F
% Gly: 0 8 8 0 0 0 0 0 72 0 8 0 8 8 8 % G
% His: 0 0 15 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 29 0 0 0 8 22 0 0 0 8 0 0 0 0 0 % I
% Lys: 36 0 0 0 0 0 0 0 0 0 29 0 0 0 0 % K
% Leu: 0 0 0 0 29 8 0 0 8 0 8 22 0 58 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 65 0 15 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 50 8 0 0 0 0 % N
% Pro: 0 86 0 79 0 0 0 8 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 8 8 0 0 0 0 0 0 0 0 0 8 0 0 79 % R
% Ser: 0 0 8 0 0 0 15 36 0 43 36 0 0 0 0 % S
% Thr: 0 0 0 0 15 8 0 50 22 0 0 0 0 0 0 % T
% Val: 0 0 0 0 36 58 0 0 0 0 0 0 0 15 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 8 0 0 0 0 22 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _