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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLL2
All Species:
31.21
Human Site:
S959
Identified Species:
52.82
UniProt:
Q9Y6L7
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6L7
NP_036597.1
1015
113557
S959
E
A
Y
D
G
Y
D
S
S
A
P
R
L
G
R
Chimpanzee
Pan troglodytes
XP_507953
1164
129143
S1108
E
A
Y
D
G
Y
D
S
S
A
P
R
L
G
R
Rhesus Macaque
Macaca mulatta
XP_001101883
1013
114718
S957
E
L
F
D
G
L
D
S
T
A
V
G
L
G
R
Dog
Lupus familis
XP_543945
1032
114883
S966
E
A
D
D
G
Y
D
S
T
F
S
G
S
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVM6
1012
113234
S956
E
A
Y
D
G
Y
D
S
S
A
P
R
L
G
R
Rat
Rattus norvegicus
XP_345032
1014
113481
S958
E
A
Y
D
G
Y
D
S
S
A
P
R
L
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509196
1014
114574
D958
E
L
F
D
G
H
D
D
S
A
T
R
L
G
R
Chicken
Gallus gallus
Q9DER7
1008
114873
K952
E
L
F
D
G
H
D
K
T
A
M
R
L
G
R
Frog
Xenopus laevis
O57382
1019
114873
S962
E
V
Y
D
G
Y
D
S
T
A
P
R
L
G
R
Zebra Danio
Brachydanio rerio
O57460
1022
115518
T966
E
L
Y
D
G
Y
D
T
G
A
H
K
I
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25723
1067
121762
S980
E
I
T
E
E
G
Y
S
M
N
T
I
H
G
R
Honey Bee
Apis mellifera
XP_393866
1225
138704
T1157
E
V
Y
S
G
L
D
T
S
G
L
L
Y
G
R
Nematode Worm
Caenorhab. elegans
Q20176
951
107516
G898
P
E
V
I
T
S
T
G
P
E
L
L
L
I
M
Sea Urchin
Strong. purpuratus
P98069
639
71875
I586
Y
S
L
V
Y
E
G
I
S
P
A
L
L
I
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.5
72.4
89.6
N.A.
90.2
89.6
N.A.
73
72.5
75
73.2
N.A.
41.5
46.2
40.6
37.8
Protein Similarity:
100
86.7
83.3
92.7
N.A.
93.8
93.9
N.A.
83.8
83
86.3
84.4
N.A.
57.4
59.8
57.6
47.9
P-Site Identity:
100
100
60
46.6
N.A.
100
100
N.A.
66.6
60
86.6
60
N.A.
26.6
46.6
6.6
13.3
P-Site Similarity:
100
100
73.3
53.3
N.A.
100
100
N.A.
80
80
93.3
80
N.A.
33.3
53.3
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
36
0
0
0
0
0
0
0
65
8
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
72
0
0
79
8
0
0
0
0
0
0
0
% D
% Glu:
86
8
0
8
8
8
0
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
22
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
79
8
8
8
8
8
0
15
0
79
0
% G
% His:
0
0
0
0
0
15
0
0
0
0
8
0
8
0
0
% H
% Ile:
0
8
0
8
0
0
0
8
0
0
0
8
8
15
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% K
% Leu:
0
29
8
0
0
15
0
0
0
0
15
22
72
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
8
8
36
0
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
50
0
0
79
% R
% Ser:
0
8
0
8
0
8
0
58
50
0
8
0
8
0
0
% S
% Thr:
0
0
8
0
8
0
8
15
29
0
15
0
0
0
0
% T
% Val:
0
15
8
8
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
50
0
8
50
8
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _