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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLL2
All Species:
7.58
Human Site:
T116
Identified Species:
12.82
UniProt:
Q9Y6L7
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6L7
NP_036597.1
1015
113557
T116
T
T
A
M
D
T
G
T
K
E
A
G
K
D
G
Chimpanzee
Pan troglodytes
XP_507953
1164
129143
T265
T
T
A
M
D
T
G
T
K
E
A
G
K
D
G
Rhesus Macaque
Macaca mulatta
XP_001101883
1013
114718
R114
A
L
Y
Q
L
I
D
R
I
R
R
I
G
F
G
Dog
Lupus familis
XP_543945
1032
114883
S123
A
A
A
N
A
S
S
S
E
E
A
G
K
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVM6
1012
113234
I113
D
T
A
S
N
A
S
I
Q
A
P
R
K
D
G
Rat
Rattus norvegicus
XP_345032
1014
113481
I115
D
T
A
S
N
S
S
I
Q
A
L
R
K
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509196
1014
114574
R115
A
L
Y
Q
L
I
D
R
I
R
R
F
G
S
G
Chicken
Gallus gallus
Q9DER7
1008
114873
R110
A
L
Y
Q
L
I
E
R
I
R
R
F
G
S
G
Frog
Xenopus laevis
O57382
1019
114873
V119
S
N
L
N
S
K
K
V
K
K
G
S
R
L
K
Zebra Danio
Brachydanio rerio
O57460
1022
115518
F123
D
R
I
R
R
L
G
F
E
S
W
P
V
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25723
1067
121762
R103
S
Q
N
K
A
A
L
R
L
P
P
P
F
L
W
Honey Bee
Apis mellifera
XP_393866
1225
138704
H303
S
D
E
V
V
S
F
H
D
R
Q
L
R
S
I
Nematode Worm
Caenorhab. elegans
Q20176
951
107516
F88
A
M
R
H
W
E
N
F
T
C
V
S
F
V
P
Sea Urchin
Strong. purpuratus
P98069
639
71875
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.5
72.4
89.6
N.A.
90.2
89.6
N.A.
73
72.5
75
73.2
N.A.
41.5
46.2
40.6
37.8
Protein Similarity:
100
86.7
83.3
92.7
N.A.
93.8
93.9
N.A.
83.8
83
86.3
84.4
N.A.
57.4
59.8
57.6
47.9
P-Site Identity:
100
100
6.6
46.6
N.A.
33.3
33.3
N.A.
6.6
6.6
6.6
6.6
N.A.
0
0
0
0
P-Site Similarity:
100
100
6.6
66.6
N.A.
46.6
53.3
N.A.
6.6
6.6
26.6
20
N.A.
6.6
26.6
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
8
36
0
15
15
0
0
0
15
22
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
22
8
0
0
15
0
15
0
8
0
0
0
0
36
0
% D
% Glu:
0
0
8
0
0
8
8
0
15
22
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
15
0
0
0
15
15
8
0
% F
% Gly:
0
0
0
0
0
0
22
0
0
0
8
22
22
0
58
% G
% His:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
22
0
15
22
0
0
8
0
0
8
% I
% Lys:
0
0
0
8
0
8
8
0
22
8
0
0
36
0
8
% K
% Leu:
0
22
8
0
22
8
8
0
8
0
8
8
0
15
0
% L
% Met:
0
8
0
15
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
15
15
0
8
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
15
15
0
0
8
% P
% Gln:
0
8
0
22
0
0
0
0
15
0
8
0
0
0
0
% Q
% Arg:
0
8
8
8
8
0
0
29
0
29
22
15
15
0
0
% R
% Ser:
22
0
0
15
8
22
22
8
0
8
0
15
0
22
8
% S
% Thr:
15
29
0
0
0
15
0
15
8
0
0
0
0
0
0
% T
% Val:
0
0
0
8
8
0
0
8
0
0
8
0
8
8
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
8
% W
% Tyr:
0
0
22
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _