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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLL2
All Species:
37.27
Human Site:
T937
Identified Species:
63.08
UniProt:
Q9Y6L7
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6L7
NP_036597.1
1015
113557
T937
G
V
E
L
T
F
R
T
F
E
V
E
E
E
A
Chimpanzee
Pan troglodytes
XP_507953
1164
129143
T1086
G
V
E
L
T
F
R
T
F
E
V
E
E
E
A
Rhesus Macaque
Macaca mulatta
XP_001101883
1013
114718
T935
R
L
E
L
S
F
Q
T
F
E
V
E
E
E
A
Dog
Lupus familis
XP_543945
1032
114883
I944
G
A
E
L
I
F
R
I
F
E
E
E
E
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVM6
1012
113234
T934
G
V
E
L
I
F
R
T
F
E
V
E
E
E
A
Rat
Rattus norvegicus
XP_345032
1014
113481
T936
G
V
E
L
V
F
R
T
F
E
V
E
E
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509196
1014
114574
T936
R
V
E
L
T
F
Q
T
F
E
V
E
E
E
A
Chicken
Gallus gallus
Q9DER7
1008
114873
T930
R
V
E
L
M
F
Q
T
F
E
V
E
E
E
A
Frog
Xenopus laevis
O57382
1019
114873
T940
G
V
E
L
I
F
Q
T
F
E
I
E
E
E
S
Zebra Danio
Brachydanio rerio
O57460
1022
115518
T944
G
I
E
L
T
F
T
T
F
E
V
E
E
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25723
1067
121762
H958
S
V
K
I
R
F
L
H
F
E
I
E
Y
S
E
Honey Bee
Apis mellifera
XP_393866
1225
138704
T1135
N
V
H
L
T
F
V
T
F
Q
L
E
S
E
S
Nematode Worm
Caenorhab. elegans
Q20176
951
107516
A876
E
I
Y
D
G
P
E
A
T
L
E
R
L
V
G
Sea Urchin
Strong. purpuratus
P98069
639
71875
E564
C
D
C
R
P
G
Y
E
L
S
S
D
G
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.5
72.4
89.6
N.A.
90.2
89.6
N.A.
73
72.5
75
73.2
N.A.
41.5
46.2
40.6
37.8
Protein Similarity:
100
86.7
83.3
92.7
N.A.
93.8
93.9
N.A.
83.8
83
86.3
84.4
N.A.
57.4
59.8
57.6
47.9
P-Site Identity:
100
100
73.3
73.3
N.A.
93.3
93.3
N.A.
86.6
80
73.3
86.6
N.A.
33.3
53.3
0
0
P-Site Similarity:
100
100
93.3
73.3
N.A.
93.3
93.3
N.A.
93.3
86.6
93.3
93.3
N.A.
53.3
73.3
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
65
% A
% Cys:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
8
0
72
0
0
0
8
8
0
79
15
86
72
79
8
% E
% Phe:
0
0
0
0
0
86
0
0
86
0
0
0
0
0
0
% F
% Gly:
50
0
0
0
8
8
0
0
0
0
0
0
8
0
8
% G
% His:
0
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
15
0
8
22
0
0
8
0
0
15
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
8
0
79
0
0
8
0
8
8
8
0
8
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
29
0
0
8
0
0
0
0
0
% Q
% Arg:
22
0
0
8
8
0
36
0
0
0
0
8
0
8
8
% R
% Ser:
8
0
0
0
8
0
0
0
0
8
8
0
8
8
15
% S
% Thr:
0
0
0
0
36
0
8
72
8
0
0
0
0
0
0
% T
% Val:
0
65
0
0
8
0
8
0
0
0
58
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _