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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TLL2 All Species: 41.21
Human Site: Y408 Identified Species: 69.74
UniProt: Q9Y6L7 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6L7 NP_036597.1 1015 113557 Y408 S R L C W Y D Y V E V R D G Y
Chimpanzee Pan troglodytes XP_507953 1164 129143 Y557 S R L C W Y D Y V E V R D G Y
Rhesus Macaque Macaca mulatta XP_001101883 1013 114718 Y406 S S L C W Y D Y I E V R D G Y
Dog Lupus familis XP_543945 1032 114883 Y415 S R L C W Y D Y V E V R D G Y
Cat Felis silvestris
Mouse Mus musculus Q9WVM6 1012 113234 Y405 S R L C W Y D Y V E I R D G Y
Rat Rattus norvegicus XP_345032 1014 113481 Y407 S R L C W Y D Y V E I R D G Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509196 1014 114574 Y407 S S L C W Y D Y I E V R D G Y
Chicken Gallus gallus Q9DER7 1008 114873 Y402 S S L C W Y D Y I E V R D G Y
Frog Xenopus laevis O57382 1019 114873 Y411 S R L C W Y D Y I E I R D G Y
Zebra Danio Brachydanio rerio O57460 1022 115518 Y415 S S L C W Y D Y I E V R D G Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25723 1067 121762 T397 C E W R I T A T N G E K V I L
Honey Bee Apis mellifera XP_393866 1225 138704 S597 F K S N F C R S D Y L E I R D
Nematode Worm Caenorhab. elegans Q20176 951 107516 T368 L I Q V R S S T P A A S L P F
Sea Urchin Strong. purpuratus P98069 639 71875 E56 T E D D Y E R E M I R A R H N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.5 72.4 89.6 N.A. 90.2 89.6 N.A. 73 72.5 75 73.2 N.A. 41.5 46.2 40.6 37.8
Protein Similarity: 100 86.7 83.3 92.7 N.A. 93.8 93.9 N.A. 83.8 83 86.3 84.4 N.A. 57.4 59.8 57.6 47.9
P-Site Identity: 100 100 86.6 100 N.A. 93.3 93.3 N.A. 86.6 86.6 86.6 86.6 N.A. 0 0 0 0
P-Site Similarity: 100 100 93.3 100 N.A. 100 100 N.A. 93.3 93.3 100 93.3 N.A. 6.6 20 6.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 0 0 8 8 8 0 0 0 % A
% Cys: 8 0 0 72 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 8 0 0 72 0 8 0 0 0 72 0 8 % D
% Glu: 0 15 0 0 0 8 0 8 0 72 8 8 0 0 0 % E
% Phe: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 0 0 0 0 0 0 8 0 0 0 72 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 8 0 0 8 0 0 0 36 8 22 0 8 8 0 % I
% Lys: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % K
% Leu: 8 0 72 0 0 0 0 0 0 0 8 0 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 43 0 8 8 0 15 0 0 0 8 72 8 8 0 % R
% Ser: 72 29 8 0 0 8 8 8 0 0 0 8 0 0 0 % S
% Thr: 8 0 0 0 0 8 0 15 0 0 0 0 0 0 0 % T
% Val: 0 0 0 8 0 0 0 0 36 0 50 0 8 0 0 % V
% Trp: 0 0 8 0 72 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 72 0 72 0 8 0 0 0 0 72 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _