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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRSS21
All Species:
4.55
Human Site:
S122
Identified Species:
14.29
UniProt:
Q9Y6M0
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6M0
NP_006790.1
314
34884
S122
Y
Y
T
R
Y
F
V
S
N
I
Y
L
S
P
R
Chimpanzee
Pan troglodytes
XP_523489
236
26621
D65
A
L
G
V
L
R
N
D
I
A
L
L
R
L
A
Rhesus Macaque
Macaca mulatta
XP_001087762
396
44009
S204
Y
Y
T
R
Y
F
V
S
N
I
Y
L
S
P
R
Dog
Lupus familis
XP_536999
287
32167
A110
L
S
P
M
Y
L
G
A
S
S
Y
D
I
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHJ7
324
36157
E132
Y
S
N
R
Y
Q
I
E
D
I
F
L
S
P
K
Rat
Rattus norvegicus
Q6BEA2
328
35785
R112
A
L
Y
V
P
V
K
R
V
K
S
H
P
E
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514436
385
42176
V109
L
R
L
S
V
A
E
V
R
P
H
P
V
Y
A
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001081364
389
42357
F106
S
I
T
K
H
P
D
F
Q
Y
E
G
S
S
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.4
70.7
60.5
N.A.
64.8
42.6
N.A.
36.3
N.A.
34.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
54.1
75
75.1
N.A.
77.7
57
N.A.
49.6
N.A.
49.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
13.3
N.A.
46.6
0
N.A.
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
26.6
N.A.
73.3
0
N.A.
6.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
0
0
0
0
13
0
13
0
13
0
0
0
13
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
13
13
13
0
0
13
0
0
0
% D
% Glu:
0
0
0
0
0
0
13
13
0
0
13
0
0
13
0
% E
% Phe:
0
0
0
0
0
25
0
13
0
0
13
0
0
0
0
% F
% Gly:
0
0
13
0
0
0
13
0
0
0
0
13
0
0
13
% G
% His:
0
0
0
0
13
0
0
0
0
0
13
13
0
0
0
% H
% Ile:
0
13
0
0
0
0
13
0
13
38
0
0
13
0
0
% I
% Lys:
0
0
0
13
0
0
13
0
0
13
0
0
0
0
13
% K
% Leu:
25
25
13
0
13
13
0
0
0
0
13
50
0
13
13
% L
% Met:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
0
13
0
25
0
0
0
0
0
0
% N
% Pro:
0
0
13
0
13
13
0
0
0
13
0
13
13
38
0
% P
% Gln:
0
0
0
0
0
13
0
0
13
0
0
0
0
0
0
% Q
% Arg:
0
13
0
38
0
13
0
13
13
0
0
0
13
0
25
% R
% Ser:
13
25
0
13
0
0
0
25
13
13
13
0
50
13
0
% S
% Thr:
0
0
38
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
25
13
13
25
13
13
0
0
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
38
25
13
0
50
0
0
0
0
13
38
0
0
13
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _