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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IGF2BP2
All Species:
11.82
Human Site:
S407
Identified Species:
28.89
UniProt:
Q9Y6M1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6M1
NP_001007226.1
599
66121
S407
T
T
H
S
G
Y
F
S
S
L
Y
P
H
H
Q
Chimpanzee
Pan troglodytes
XP_001151172
576
63413
P391
A
G
P
R
G
A
P
P
A
A
P
Y
H
P
F
Rhesus Macaque
Macaca mulatta
XP_001095336
599
66059
S407
A
T
H
S
G
Y
F
S
S
L
Y
P
H
H
Q
Dog
Lupus familis
XP_535832
526
57878
P362
E
I
V
N
L
F
I
P
T
Q
A
V
G
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q5SF07
592
65565
S400
A
T
H
S
G
Y
F
S
S
L
Y
P
H
H
H
Rat
Rattus norvegicus
Q8CGX0
577
63418
A394
P
S
S
V
T
G
A
A
P
Y
G
S
F
M
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516066
840
89620
S646
A
S
H
S
P
Y
L
S
G
L
Y
G
A
S
R
Chicken
Gallus gallus
O42254
576
63253
A393
P
P
S
S
V
S
G
A
A
P
Y
S
S
F
M
Frog
Xenopus laevis
O57526
593
65367
T403
S
A
G
V
S
S
P
T
T
S
A
S
Y
P
P
Zebra Danio
Brachydanio rerio
Q08CK7
598
65511
G396
A
L
G
N
S
V
P
G
P
P
Y
G
P
M
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
99.6
86.3
N.A.
94.6
65.7
N.A.
57.6
66.7
69.2
67.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.1
99.8
87.1
N.A.
96.8
80.3
N.A.
63.4
79.6
81.3
81.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
93.3
0
N.A.
86.6
6.6
N.A.
40
13.3
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
93.3
20
N.A.
86.6
20
N.A.
53.3
26.6
26.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
10
0
0
0
10
10
20
20
10
20
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
30
0
0
0
0
0
10
10
10
% F
% Gly:
0
10
20
0
40
10
10
10
10
0
10
20
10
0
10
% G
% His:
0
0
40
0
0
0
0
0
0
0
0
0
40
30
10
% H
% Ile:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
10
0
10
0
0
40
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
10
% M
% Asn:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
20
10
10
0
10
0
30
20
20
20
10
30
10
20
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
30
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% R
% Ser:
10
20
20
50
20
20
0
40
30
10
0
30
10
10
0
% S
% Thr:
10
30
0
0
10
0
0
10
20
0
0
0
0
0
0
% T
% Val:
0
0
10
20
10
10
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
40
0
0
0
10
60
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _