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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IGF2BP2
All Species:
12.73
Human Site:
Y410
Identified Species:
31.11
UniProt:
Q9Y6M1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6M1
NP_001007226.1
599
66121
Y410
S
G
Y
F
S
S
L
Y
P
H
H
Q
F
G
P
Chimpanzee
Pan troglodytes
XP_001151172
576
63413
P394
R
G
A
P
P
A
A
P
Y
H
P
F
T
Q
Y
Rhesus Macaque
Macaca mulatta
XP_001095336
599
66059
Y410
S
G
Y
F
S
S
L
Y
P
H
H
Q
F
G
P
Dog
Lupus familis
XP_535832
526
57878
A365
N
L
F
I
P
T
Q
A
V
G
A
I
I
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q5SF07
592
65565
Y403
S
G
Y
F
S
S
L
Y
P
H
H
H
F
G
P
Rat
Rattus norvegicus
Q8CGX0
577
63418
G397
V
T
G
A
A
P
Y
G
S
F
M
Q
A
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516066
840
89620
Y649
S
P
Y
L
S
G
L
Y
G
A
S
R
V
G
A
Chicken
Gallus gallus
O42254
576
63253
Y396
S
V
S
G
A
A
P
Y
S
S
F
M
P
P
E
Frog
Xenopus laevis
O57526
593
65367
A406
V
S
S
P
T
T
S
A
S
Y
P
P
F
G
Q
Zebra Danio
Brachydanio rerio
Q08CK7
598
65511
Y399
N
S
V
P
G
P
P
Y
G
P
M
G
A
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
99.6
86.3
N.A.
94.6
65.7
N.A.
57.6
66.7
69.2
67.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.1
99.8
87.1
N.A.
96.8
80.3
N.A.
63.4
79.6
81.3
81.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
6.6
N.A.
93.3
6.6
N.A.
40
13.3
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
26.6
N.A.
93.3
13.3
N.A.
46.6
26.6
33.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
20
20
10
20
0
10
10
0
20
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
30
% E
% Phe:
0
0
10
30
0
0
0
0
0
10
10
10
40
0
0
% F
% Gly:
0
40
10
10
10
10
0
10
20
10
0
10
0
60
0
% G
% His:
0
0
0
0
0
0
0
0
0
40
30
10
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
10
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
10
0
10
0
0
40
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
20
10
0
0
0
% M
% Asn:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
30
20
20
20
10
30
10
20
10
10
20
30
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
30
0
10
10
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
50
20
20
0
40
30
10
0
30
10
10
0
0
10
0
% S
% Thr:
0
10
0
0
10
20
0
0
0
0
0
0
10
0
0
% T
% Val:
20
10
10
0
0
0
0
0
10
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
40
0
0
0
10
60
10
10
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _