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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IGF2BP2
All Species:
10
Human Site:
Y424
Identified Species:
24.44
UniProt:
Q9Y6M1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6M1
NP_001007226.1
599
66121
Y424
P
F
P
H
H
H
S
Y
P
E
Q
E
I
V
N
Chimpanzee
Pan troglodytes
XP_001151172
576
63413
N408
Y
P
E
Q
E
I
V
N
L
F
I
P
T
Q
A
Rhesus Macaque
Macaca mulatta
XP_001095336
599
66059
Y424
P
F
P
H
H
H
S
Y
P
E
Q
E
V
V
N
Dog
Lupus familis
XP_535832
526
57878
Q379
K
K
G
A
H
I
K
Q
L
A
R
F
A
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q5SF07
592
65565
Y417
P
F
P
H
H
H
S
Y
P
E
Q
E
T
V
S
Rat
Rattus norvegicus
Q8CGX0
577
63418
F411
E
Q
E
M
V
Q
V
F
I
P
A
Q
A
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516066
840
89620
V663
A
F
P
H
Q
H
S
V
P
E
Q
E
V
V
N
Chicken
Gallus gallus
O42254
576
63253
F410
E
Q
E
T
V
H
V
F
I
P
A
Q
A
V
G
Frog
Xenopus laevis
O57526
593
65367
V420
Q
Q
P
E
S
E
T
V
H
L
F
I
P
A
L
Zebra Danio
Brachydanio rerio
Q08CK7
598
65511
Y413
E
Q
E
T
V
H
V
Y
I
P
A
Q
A
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.1
99.6
86.3
N.A.
94.6
65.7
N.A.
57.6
66.7
69.2
67.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.1
99.8
87.1
N.A.
96.8
80.3
N.A.
63.4
79.6
81.3
81.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
93.3
6.6
N.A.
86.6
6.6
N.A.
73.3
13.3
6.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
100
13.3
N.A.
93.3
20
N.A.
80
26.6
13.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
0
0
0
0
10
30
0
40
10
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
30
0
40
10
10
10
0
0
0
40
0
40
0
0
0
% E
% Phe:
0
40
0
0
0
0
0
20
0
10
10
10
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
30
% G
% His:
0
0
0
40
40
60
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
20
0
0
30
0
10
10
10
0
0
% I
% Lys:
10
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
20
10
0
0
0
0
10
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
30
% N
% Pro:
30
10
50
0
0
0
0
0
40
30
0
10
10
0
0
% P
% Gln:
10
40
0
10
10
10
0
10
0
0
40
30
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
40
0
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
20
0
0
10
0
0
0
0
0
20
0
0
% T
% Val:
0
0
0
0
30
0
40
20
0
0
0
0
20
70
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _