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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LAMC3
All Species:
7.58
Human Site:
S1459
Identified Species:
20.83
UniProt:
Q9Y6N6
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6N6
NP_006050.3
1587
172458
S1459
A
S
Q
Q
V
L
A
S
E
A
R
R
Q
E
L
Chimpanzee
Pan troglodytes
XP_001162648
1609
177614
L1475
L
Q
E
A
E
K
E
L
K
R
K
Q
D
D
A
Rhesus Macaque
Macaca mulatta
XP_001118580
1235
133120
L1114
S
E
A
R
R
Q
E
L
E
E
A
E
Q
V
G
Dog
Lupus familis
XP_548411
1492
162451
S1364
A
S
Q
Q
V
L
A
S
G
D
R
R
Q
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0B6
1581
172299
S1455
A
S
R
L
L
L
T
S
E
A
H
K
Q
E
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516008
1722
189393
E1585
M
K
Q
L
Q
E
A
E
K
E
L
Q
K
K
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LVF0
1593
176187
A1455
M
M
D
Q
L
T
A
A
E
K
E
L
E
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P15215
1639
182321
M1504
H
R
V
K
L
T
E
M
D
I
F
K
L
E
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18823
1535
170219
Q1411
L
D
D
I
I
D
A
Q
D
K
R
R
N
S
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.4
35.2
75.9
N.A.
74.5
N.A.
N.A.
41.9
N.A.
N.A.
43.1
N.A.
36.2
N.A.
35.5
N.A.
Protein Similarity:
100
60.7
42.6
82.2
N.A.
82.9
N.A.
N.A.
57.6
N.A.
N.A.
59.2
N.A.
52.5
N.A.
53.6
N.A.
P-Site Identity:
100
0
13.3
86.6
N.A.
60
N.A.
N.A.
13.3
N.A.
N.A.
20
N.A.
6.6
N.A.
26.6
N.A.
P-Site Similarity:
100
33.3
26.6
86.6
N.A.
80
N.A.
N.A.
40
N.A.
N.A.
46.6
N.A.
33.3
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
12
12
0
0
56
12
0
23
12
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
23
0
0
12
0
0
23
12
0
0
12
12
0
% D
% Glu:
0
12
12
0
12
12
34
12
45
23
12
12
12
45
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
12
% G
% His:
12
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% H
% Ile:
0
0
0
12
12
0
0
0
0
12
0
0
0
0
0
% I
% Lys:
0
12
0
12
0
12
0
0
23
23
12
23
12
23
12
% K
% Leu:
23
0
0
23
34
34
0
23
0
0
12
12
12
0
45
% L
% Met:
23
12
0
0
0
0
0
12
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
12
34
34
12
12
0
12
0
0
0
23
45
0
12
% Q
% Arg:
0
12
12
12
12
0
0
0
0
12
34
34
0
0
0
% R
% Ser:
12
34
0
0
0
0
0
34
0
0
0
0
0
12
0
% S
% Thr:
0
0
0
0
0
23
12
0
0
0
0
0
0
0
0
% T
% Val:
0
0
12
0
23
0
0
0
0
0
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _