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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USH1C All Species: 14.24
Human Site: S280 Identified Species: 52.22
UniProt: Q9Y6N9 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6N9 NP_005700.2 552 62211 S280 E A V N V L K S S R S L T I S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001085522 1395 155419 S670 E A V N V L K S S R S L T I S
Dog Lupus familis XP_852180 515 57517 S251 S S R S L T I S I V A G A G R
Cat Felis silvestris
Mouse Mus musculus Q9ES64 910 102266 S280 E A V N V L K S S R S L T I S
Rat Rattus norvegicus Q810W9 920 98326 S347 E A V K L L K S S R H L I L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509847 767 85465 A293 E A V S V L K A S R S L T L S
Chicken Gallus gallus
Frog Xenopus laevis NP_001089894 541 60891 G283 E A V R V L K G S R S L T I T
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 38.7 88.9 N.A. 58 21.5 N.A. 49.5 N.A. 70.4 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 39 90.5 N.A. 59.1 34.6 N.A. 59.4 N.A. 83.5 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 6.6 N.A. 100 60 N.A. 80 N.A. 80 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 33.3 N.A. 100 80 N.A. 100 N.A. 86.6 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 86 0 0 0 0 0 15 0 0 15 0 15 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 86 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 15 0 0 0 15 0 15 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 15 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 15 0 15 0 0 0 15 58 0 % I
% Lys: 0 0 0 15 0 0 86 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 29 86 0 0 0 0 0 86 0 29 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 43 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 15 15 0 0 0 0 0 86 0 0 0 0 15 % R
% Ser: 15 15 0 29 0 0 0 72 86 0 72 0 0 0 58 % S
% Thr: 0 0 0 0 0 15 0 0 0 0 0 0 72 0 29 % T
% Val: 0 0 86 0 72 0 0 0 0 15 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _