KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAPN6
All Species:
27.88
Human Site:
Y540
Identified Species:
55.76
UniProt:
Q9Y6Q1
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6Q1
NP_055104.2
641
74576
Y540
A
N
E
T
V
N
P
Y
L
V
I
K
C
G
K
Chimpanzee
Pan troglodytes
XP_001146965
641
74541
Y540
A
N
E
T
V
N
P
Y
L
V
I
K
C
G
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_549188
641
74596
Y540
A
N
E
T
V
N
P
Y
L
V
I
K
C
G
K
Cat
Felis silvestris
Mouse
Mus musculus
O35646
641
74510
Y540
A
N
E
T
V
N
P
Y
L
I
I
K
C
G
K
Rat
Rattus norvegicus
O88501
641
74542
Y540
A
N
E
T
V
N
P
Y
L
T
I
K
C
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518356
408
46381
Y307
S
P
S
G
A
D
S
Y
V
I
I
K
C
E
G
Chicken
Gallus gallus
Q92177
810
93542
K620
D
A
G
K
D
G
E
K
T
H
V
D
E
K
K
Frog
Xenopus laevis
NP_001080808
642
73235
Y541
S
D
G
G
A
D
P
Y
V
I
I
S
C
E
G
Zebra Danio
Brachydanio rerio
XP_001345114
642
73723
Y541
A
N
G
A
S
D
P
Y
V
I
I
T
C
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q11002
828
93944
E598
S
I
A
G
K
D
M
E
V
D
W
M
E
L
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22036
648
73596
F539
L
T
I
H
G
V
D
F
N
S
A
S
T
G
T
Sea Urchin
Strong. purpuratus
XP_001178522
642
72459
Y541
F
G
G
G
A
D
P
Y
V
Y
V
K
C
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
N.A.
97.1
N.A.
95
95
N.A.
29
28.5
46.7
47.8
N.A.
28.3
N.A.
36.4
40
Protein Similarity:
100
99.5
N.A.
98.7
N.A.
98.2
97.8
N.A.
43.2
46.2
66.1
66.9
N.A.
45.2
N.A.
55
59.9
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
26.6
6.6
26.6
40
N.A.
6.6
N.A.
6.6
26.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
93.3
N.A.
53.3
13.3
60
60
N.A.
26.6
N.A.
13.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
9
9
9
25
0
0
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
75
0
0
% C
% Asp:
9
9
0
0
9
42
9
0
0
9
0
9
0
0
0
% D
% Glu:
0
0
42
0
0
0
9
9
0
0
0
0
17
34
0
% E
% Phe:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
9
34
34
9
9
0
0
0
0
0
0
0
50
34
% G
% His:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
9
9
0
0
0
0
0
0
34
67
0
0
0
0
% I
% Lys:
0
0
0
9
9
0
0
9
0
0
0
59
0
9
59
% K
% Leu:
9
0
0
0
0
0
0
0
42
0
0
0
0
9
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% M
% Asn:
0
50
0
0
0
42
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
9
0
0
0
0
67
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
25
0
9
0
9
0
9
0
0
9
0
17
0
0
0
% S
% Thr:
0
9
0
42
0
0
0
0
9
9
0
9
9
0
9
% T
% Val:
0
0
0
0
42
9
0
0
42
25
17
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
75
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _