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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CAPN6 All Species: 20.91
Human Site: Y612 Identified Species: 41.82
UniProt: Q9Y6Q1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6Q1 NP_055104.2 641 74576 Y612 C R D L K S L Y L R K K G G P
Chimpanzee Pan troglodytes XP_001146965 641 74541 Y612 C R D L K S L Y L R K K G G P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_549188 641 74596 Y612 C R D L K S L Y L R K K G G P
Cat Felis silvestris
Mouse Mus musculus O35646 641 74510 Y612 C R D L K S L Y L R K K G G P
Rat Rattus norvegicus O88501 641 74542 Y612 C R D L K S L Y L R K K G G P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518356 408 46381 H379 P R A P H T L H L Q D R S S K
Chicken Gallus gallus Q92177 810 93542 L692 S S R S M I A L M D T D G S G
Frog Xenopus laevis NP_001080808 642 73235 E613 L Q T Q H S L E L Q N K G N K
Zebra Danio Brachydanio rerio XP_001345114 642 73723 Y613 R Q E Q H T V Y L K D K G S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q11002 828 93944 D670 E E Q L G M N D Q S N K R L I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22036 648 73596 A611 L A Q S V I I A L I D N E N R
Sea Urchin Strong. purpuratus XP_001178522 642 72459 V613 Q P E H N V A V L K K R G R D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 N.A. 97.1 N.A. 95 95 N.A. 29 28.5 46.7 47.8 N.A. 28.3 N.A. 36.4 40
Protein Similarity: 100 99.5 N.A. 98.7 N.A. 98.2 97.8 N.A. 43.2 46.2 66.1 66.9 N.A. 45.2 N.A. 55 59.9
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 20 6.6 33.3 26.6 N.A. 13.3 N.A. 6.6 20
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 46.6 13.3 46.6 60 N.A. 13.3 N.A. 13.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 0 0 0 17 9 0 0 0 0 0 0 0 % A
% Cys: 42 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 42 0 0 0 0 9 0 9 25 9 0 0 9 % D
% Glu: 9 9 17 0 0 0 0 9 0 0 0 0 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 9 0 0 0 0 0 0 0 75 42 9 % G
% His: 0 0 0 9 25 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 17 9 0 0 9 0 0 0 0 9 % I
% Lys: 0 0 0 0 42 0 0 0 0 17 50 67 0 0 17 % K
% Leu: 17 0 0 50 0 0 59 9 84 0 0 0 0 9 0 % L
% Met: 0 0 0 0 9 9 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 9 0 0 0 17 9 0 17 0 % N
% Pro: 9 9 0 9 0 0 0 0 0 0 0 0 0 0 42 % P
% Gln: 9 17 17 17 0 0 0 0 9 17 0 0 0 0 0 % Q
% Arg: 9 50 9 0 0 0 0 0 0 42 0 17 9 9 17 % R
% Ser: 9 9 0 17 0 50 0 0 0 9 0 0 9 25 0 % S
% Thr: 0 0 9 0 0 17 0 0 0 0 9 0 0 0 0 % T
% Val: 0 0 0 0 9 9 9 9 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _