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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP1M2
All Species:
22.73
Human Site:
Y166
Identified Species:
50
UniProt:
Q9Y6Q5
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6Q5
NP_005489.2
423
48108
Y166
W
R
S
E
G
I
K
Y
K
K
N
E
V
F
I
Chimpanzee
Pan troglodytes
XP_001165482
423
48062
Y166
W
R
S
E
G
I
K
Y
K
K
N
E
V
F
I
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853941
421
47786
Y164
W
R
S
E
G
L
K
Y
K
K
N
E
V
F
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVP1
423
48118
Y166
W
R
S
E
G
I
K
Y
K
K
N
E
V
F
I
Rat
Rattus norvegicus
Q32Q06
423
48538
Y166
W
R
S
E
G
I
K
Y
R
K
N
E
V
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZMP6
433
49371
I164
I
G
W
R
R
E
G
I
K
Y
R
R
N
E
L
Frog
Xenopus laevis
Q801Q8
435
49666
E164
G
Q
I
G
W
R
R
E
G
I
K
Y
R
R
N
Zebra Danio
Brachydanio rerio
Q7ZW98
436
49724
E164
G
Q
I
G
W
R
R
E
G
I
K
Y
R
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649906
426
48922
Y168
W
R
S
E
G
I
K
Y
R
K
N
E
V
F
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P35602
422
48210
R166
R
S
E
G
I
K
Y
R
K
N
E
V
F
L
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q00776
475
53855
R167
L
T
N
S
V
S
W
R
P
E
G
I
T
H
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
95
N.A.
96.9
79.6
N.A.
N.A.
39.4
39
38.7
N.A.
75.3
N.A.
69.7
N.A.
Protein Similarity:
100
100
N.A.
96.9
N.A.
98.8
91.9
N.A.
N.A.
63.2
62.7
62.8
N.A.
88.9
N.A.
86.2
N.A.
P-Site Identity:
100
100
N.A.
93.3
N.A.
100
86.6
N.A.
N.A.
6.6
0
0
N.A.
86.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
13.3
13.3
13.3
N.A.
100
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
50.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
69.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
10
55
0
10
0
19
0
10
10
55
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
55
0
% F
% Gly:
19
10
0
28
55
0
10
0
19
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
10
0
19
0
10
46
0
10
0
19
0
10
0
0
37
% I
% Lys:
0
0
0
0
0
10
55
0
55
55
19
0
0
0
10
% K
% Leu:
10
0
0
0
0
10
0
0
0
0
0
0
0
10
28
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
10
55
0
10
0
19
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
55
0
10
10
19
19
19
19
0
10
10
19
19
0
% R
% Ser:
0
10
55
10
0
10
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
10
55
0
0
% V
% Trp:
55
0
10
0
19
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
55
0
10
0
19
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _