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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NCOA3 All Species: 2.12
Human Site: T259 Identified Species: 4.67
UniProt: Q9Y6Q9 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6Q9 NP_006525.2 1424 155293 T259 R I T T G E R T F P S N P E S
Chimpanzee Pan troglodytes XP_515330 1411 153498 I256 R L P R P P A I T G V E S F M
Rhesus Macaque Macaca mulatta XP_001101475 1426 155295 A259 R I T T G E R A F P S N P E S
Dog Lupus familis XP_543039 1416 154250 A260 R I T T G E R A F P S N P E S
Cat Felis silvestris
Mouse Mus musculus O09000 1398 151555 S260 R V T A P F P S S P E S F I T
Rat Rattus norvegicus Q9EPU2 1082 115082 A27 Q K R H Y Q E A Y I H G H A E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506517 1655 177573 V260 R L T T V E R V F P S N P E S
Chicken Gallus gallus XP_417385 1399 152811 V261 R I A T A E R V F P T N P E S
Frog Xenopus laevis O57539 1391 152514 A260 R I T T A E R A F S A N P E S
Zebra Danio Brachydanio rerio Q98TW1 1505 161775 P261 R V P M K E R P M L P T Q E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O61735 1027 116123
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 29.4 98.1 91.8 N.A. 80.5 62.7 N.A. 68 75.8 70.3 39.5 N.A. 20.2 N.A. N.A. N.A.
Protein Similarity: 100 46.3 99 95.5 N.A. 86.6 68.4 N.A. 75.2 85.9 81.7 55.4 N.A. 34.6 N.A. N.A. N.A.
P-Site Identity: 100 6.6 93.3 93.3 N.A. 20 0 N.A. 80 73.3 73.3 33.3 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 13.3 93.3 93.3 N.A. 46.6 20 N.A. 86.6 80 80 40 N.A. 0 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 19 0 10 37 0 0 10 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 64 10 0 0 0 10 10 0 64 10 % E
% Phe: 0 0 0 0 0 10 0 0 55 0 0 0 10 10 0 % F
% Gly: 0 0 0 0 28 0 0 0 0 10 0 10 0 0 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 10 0 10 0 0 % H
% Ile: 0 46 0 0 0 0 0 10 0 10 0 0 0 10 0 % I
% Lys: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 19 0 0 0 0 0 0 0 10 0 0 0 0 0 % L
% Met: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 55 0 0 0 % N
% Pro: 0 0 19 0 19 10 10 10 0 55 10 0 55 0 0 % P
% Gln: 10 0 0 0 0 10 0 0 0 0 0 0 10 0 0 % Q
% Arg: 82 0 10 10 0 0 64 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 10 10 10 37 10 10 0 64 % S
% Thr: 0 0 55 55 0 0 0 10 10 0 10 10 0 0 10 % T
% Val: 0 19 0 0 10 0 0 19 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _