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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUMBL
All Species:
20.61
Human Site:
S305
Identified Species:
56.67
UniProt:
Q9Y6R0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6R0
NP_004747.1
609
64891
S305
E
Q
L
V
R
Q
G
S
F
R
G
F
P
A
L
Chimpanzee
Pan troglodytes
XP_524270
613
64922
G364
A
G
T
P
V
A
A
G
T
T
A
A
A
I
P
Rhesus Macaque
Macaca mulatta
XP_001091792
930
98231
S603
E
Q
L
V
R
Q
G
S
F
R
G
F
P
A
L
Dog
Lupus familis
XP_855314
690
73063
S397
E
Q
L
V
R
Q
G
S
F
R
G
F
P
A
L
Cat
Felis silvestris
Mouse
Mus musculus
O08919
604
64172
S305
E
Q
L
V
R
Q
G
S
F
R
G
F
P
A
L
Rat
Rattus norvegicus
A1L1I3
614
65494
S305
E
Q
L
V
R
Q
G
S
F
R
G
F
P
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_990166
582
63254
K276
G
F
P
A
L
S
Q
K
M
S
P
F
K
R
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16554
556
60596
N308
R
Q
M
S
L
R
I
N
D
L
P
S
N
A
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XTY6
593
65492
S335
A
L
F
L
R
Q
G
S
L
R
A
P
P
D
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.6
53.4
83.4
N.A.
94.9
94.4
N.A.
N.A.
52.8
N.A.
N.A.
N.A.
35.7
N.A.
30.7
N.A.
Protein Similarity:
100
86.3
54.7
84.6
N.A.
95.4
95.1
N.A.
N.A.
62.8
N.A.
N.A.
N.A.
47.6
N.A.
42.6
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
13.3
N.A.
40
N.A.
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
33.3
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
0
0
12
0
12
12
0
0
0
23
12
12
67
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
12
0
0
0
0
12
12
% D
% Glu:
56
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
12
12
0
0
0
0
0
56
0
0
67
0
0
0
% F
% Gly:
12
12
0
0
0
0
67
12
0
0
56
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
12
0
0
0
0
0
0
12
0
% I
% Lys:
0
0
0
0
0
0
0
12
0
0
0
0
12
0
0
% K
% Leu:
0
12
56
12
23
0
0
0
12
12
0
0
0
0
56
% L
% Met:
0
0
12
0
0
0
0
0
12
0
0
0
0
0
12
% M
% Asn:
0
0
0
0
0
0
0
12
0
0
0
0
12
0
0
% N
% Pro:
0
0
12
12
0
0
0
0
0
0
23
12
67
0
12
% P
% Gln:
0
67
0
0
0
67
12
0
0
0
0
0
0
0
12
% Q
% Arg:
12
0
0
0
67
12
0
0
0
67
0
0
0
12
0
% R
% Ser:
0
0
0
12
0
12
0
67
0
12
0
12
0
0
0
% S
% Thr:
0
0
12
0
0
0
0
0
12
12
0
0
0
0
0
% T
% Val:
0
0
0
56
12
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _