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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K4
All Species:
16.06
Human Site:
S553
Identified Species:
44.17
UniProt:
Q9Y6R4
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6R4
NP_005913.2
1607
181552
S553
L
H
K
L
M
D
G
S
L
Q
R
A
R
I
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851019
1604
181061
S554
L
H
K
L
M
D
G
S
L
Q
R
A
R
I
A
Cat
Felis silvestris
Mouse
Mus musculus
O08648
1597
179930
S544
L
H
K
L
M
N
G
S
L
Q
R
A
R
V
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512333
716
80761
Chicken
Gallus gallus
XP_419617
1576
178289
S532
L
H
K
L
M
H
G
S
L
Q
R
A
R
M
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689836
1475
168741
E508
G
P
V
E
E
E
A
E
S
G
R
V
S
W
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732373
1571
177332
S535
N
D
D
S
A
V
N
S
M
D
S
S
K
P
P
Honey Bee
Apis mellifera
XP_392650
1209
140403
V242
M
E
Y
R
Y
D
P
V
A
N
V
K
N
D
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797473
1747
197449
T612
D
H
V
E
D
D
Q
T
P
F
P
P
K
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93
N.A.
88.3
N.A.
N.A.
38.9
84.5
N.A.
67
N.A.
25.2
29.6
N.A.
36.1
Protein Similarity:
100
N.A.
N.A.
95.5
N.A.
92.4
N.A.
N.A.
41.8
90.6
N.A.
78.2
N.A.
42
47.1
N.A.
53
P-Site Identity:
100
N.A.
N.A.
100
N.A.
86.6
N.A.
N.A.
0
86.6
N.A.
6.6
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
0
93.3
N.A.
13.3
N.A.
26.6
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
12
0
12
0
12
0
0
45
0
0
45
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
12
12
0
12
45
0
0
0
12
0
0
0
12
0
% D
% Glu:
0
12
0
23
12
12
0
12
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% F
% Gly:
12
0
0
0
0
0
45
0
0
12
0
0
0
12
0
% G
% His:
0
56
0
0
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
23
0
% I
% Lys:
0
0
45
0
0
0
0
0
0
0
0
12
23
0
0
% K
% Leu:
45
0
0
45
0
0
0
0
45
0
0
0
0
0
0
% L
% Met:
12
0
0
0
45
0
0
0
12
0
0
0
0
12
0
% M
% Asn:
12
0
0
0
0
12
12
0
0
12
0
0
12
0
12
% N
% Pro:
0
12
0
0
0
0
12
0
12
0
12
12
0
12
12
% P
% Gln:
0
0
0
0
0
0
12
0
0
45
0
0
0
0
12
% Q
% Arg:
0
0
0
12
0
0
0
0
0
0
56
0
45
0
0
% R
% Ser:
0
0
0
12
0
0
0
56
12
0
12
12
12
0
12
% S
% Thr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% T
% Val:
0
0
23
0
0
12
0
12
0
0
12
12
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% W
% Tyr:
0
0
12
0
12
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _