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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAP3K4 All Species: 19.39
Human Site: S647 Identified Species: 53.33
UniProt: Q9Y6R4 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6R4 NP_005913.2 1607 181552 S647 A G E P S L L S I K Q L V R E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851019 1604 181061 S648 A G E P S L L S I K Q L V R E
Cat Felis silvestris
Mouse Mus musculus O08648 1597 179930 S638 A G E P S L L S I K Q L V R E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512333 716 80761
Chicken Gallus gallus XP_419617 1576 178289 S626 A G E P S L L S I K Q L V R E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689836 1475 168741 Y581 G G L L M K Q Y Y Q F M L R G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_732373 1571 177332 S608 M H D I N I F S V E P L G T C
Honey Bee Apis mellifera XP_392650 1209 140403 T315 L Y K S T E F T D R V K A M C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797473 1747 197449 Y693 A L T S T P Q Y R S P R T D E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 93 N.A. 88.3 N.A. N.A. 38.9 84.5 N.A. 67 N.A. 25.2 29.6 N.A. 36.1
Protein Similarity: 100 N.A. N.A. 95.5 N.A. 92.4 N.A. N.A. 41.8 90.6 N.A. 78.2 N.A. 42 47.1 N.A. 53
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 N.A. N.A. 0 100 N.A. 13.3 N.A. 13.3 0 N.A. 13.3
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 N.A. N.A. 0 100 N.A. 33.3 N.A. 46.6 26.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 56 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 23 % C
% Asp: 0 0 12 0 0 0 0 0 12 0 0 0 0 12 0 % D
% Glu: 0 0 45 0 0 12 0 0 0 12 0 0 0 0 56 % E
% Phe: 0 0 0 0 0 0 23 0 0 0 12 0 0 0 0 % F
% Gly: 12 56 0 0 0 0 0 0 0 0 0 0 12 0 12 % G
% His: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 12 0 12 0 0 45 0 0 0 0 0 0 % I
% Lys: 0 0 12 0 0 12 0 0 0 45 0 12 0 0 0 % K
% Leu: 12 12 12 12 0 45 45 0 0 0 0 56 12 0 0 % L
% Met: 12 0 0 0 12 0 0 0 0 0 0 12 0 12 0 % M
% Asn: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 45 0 12 0 0 0 0 23 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 23 0 0 12 45 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 12 12 0 12 0 56 0 % R
% Ser: 0 0 0 23 45 0 0 56 0 12 0 0 0 0 0 % S
% Thr: 0 0 12 0 23 0 0 12 0 0 0 0 12 12 0 % T
% Val: 0 0 0 0 0 0 0 0 12 0 12 0 45 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 12 0 0 0 0 0 23 12 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _