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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K4
All Species:
10
Human Site:
S892
Identified Species:
27.5
UniProt:
Q9Y6R4
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6R4
NP_005913.2
1607
181552
S892
G
K
D
C
S
K
D
S
D
D
V
L
I
D
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851019
1604
181061
S893
G
K
D
C
S
K
E
S
D
D
V
L
I
D
A
Cat
Felis silvestris
Mouse
Mus musculus
O08648
1597
179930
P883
G
K
D
C
S
K
D
P
D
D
V
F
M
D
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512333
716
80761
E27
D
D
S
S
G
E
K
E
R
D
F
W
T
K
D
Chicken
Gallus gallus
XP_419617
1576
178289
S871
G
K
D
C
S
K
D
S
D
E
V
A
Y
E
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689836
1475
168741
E786
F
V
P
C
D
L
T
E
Q
R
L
V
I
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732373
1571
177332
L830
E
G
N
Q
K
S
V
L
E
K
E
W
M
F
T
Honey Bee
Apis mellifera
XP_392650
1209
140403
G520
L
M
R
E
L
R
E
G
L
R
I
A
C
I
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797473
1747
197449
Y917
L
Q
E
M
L
Q
V
Y
F
E
Y
V
H
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93
N.A.
88.3
N.A.
N.A.
38.9
84.5
N.A.
67
N.A.
25.2
29.6
N.A.
36.1
Protein Similarity:
100
N.A.
N.A.
95.5
N.A.
92.4
N.A.
N.A.
41.8
90.6
N.A.
78.2
N.A.
42
47.1
N.A.
53
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
80
N.A.
N.A.
6.6
73.3
N.A.
13.3
N.A.
0
0
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
86.6
N.A.
N.A.
13.3
86.6
N.A.
26.6
N.A.
20
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
23
0
0
45
% A
% Cys:
0
0
0
56
0
0
0
0
0
0
0
0
12
0
0
% C
% Asp:
12
12
45
0
12
0
34
0
45
45
0
0
0
34
12
% D
% Glu:
12
0
12
12
0
12
23
23
12
23
12
0
0
12
0
% E
% Phe:
12
0
0
0
0
0
0
0
12
0
12
12
0
12
0
% F
% Gly:
45
12
0
0
12
0
0
12
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
12
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
12
0
34
12
0
% I
% Lys:
0
45
0
0
12
45
12
0
0
12
0
0
0
12
0
% K
% Leu:
23
0
0
0
23
12
0
12
12
0
12
23
0
12
0
% L
% Met:
0
12
0
12
0
0
0
0
0
0
0
0
23
0
0
% M
% Asn:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
12
0
0
0
0
12
0
0
0
0
0
0
0
% P
% Gln:
0
12
0
12
0
12
0
0
12
0
0
0
0
0
12
% Q
% Arg:
0
0
12
0
0
12
0
0
12
23
0
0
0
0
12
% R
% Ser:
0
0
12
12
45
12
0
34
0
0
0
0
0
12
0
% S
% Thr:
0
0
0
0
0
0
12
0
0
0
0
0
12
0
12
% T
% Val:
0
12
0
0
0
0
23
0
0
0
45
23
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
23
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
12
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _