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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K4
All Species:
2.12
Human Site:
T1176
Identified Species:
5.83
UniProt:
Q9Y6R4
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6R4
NP_005913.2
1607
181552
T1176
P
T
P
E
G
F
S
T
R
S
M
P
S
D
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851019
1604
181061
S1172
I
P
T
P
E
G
F
S
T
R
S
V
P
S
D
Cat
Felis silvestris
Mouse
Mus musculus
O08648
1597
179930
S1165
P
E
G
F
S
T
R
S
V
P
S
D
A
R
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512333
716
80761
F300
S
A
L
P
E
D
D
F
L
S
L
Q
A
L
M
Chicken
Gallus gallus
XP_419617
1576
178289
H1144
H
S
D
P
P
N
P
H
L
I
I
P
T
P
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689836
1475
168741
A1059
P
V
S
S
M
Y
F
A
G
P
R
N
S
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732373
1571
177332
T1115
I
S
H
V
I
G
I
T
S
E
P
E
K
V
A
Honey Bee
Apis mellifera
XP_392650
1209
140403
E793
T
K
H
L
T
D
E
E
F
E
E
L
K
T
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797473
1747
197449
I1217
C
E
T
L
V
A
A
I
C
Q
V
E
E
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93
N.A.
88.3
N.A.
N.A.
38.9
84.5
N.A.
67
N.A.
25.2
29.6
N.A.
36.1
Protein Similarity:
100
N.A.
N.A.
95.5
N.A.
92.4
N.A.
N.A.
41.8
90.6
N.A.
78.2
N.A.
42
47.1
N.A.
53
P-Site Identity:
100
N.A.
N.A.
0
N.A.
6.6
N.A.
N.A.
6.6
6.6
N.A.
13.3
N.A.
13.3
0
N.A.
0
P-Site Similarity:
100
N.A.
N.A.
6.6
N.A.
20
N.A.
N.A.
20
26.6
N.A.
20
N.A.
20
0
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
12
12
12
0
0
0
0
23
0
23
% A
% Cys:
12
0
0
0
0
0
0
0
12
0
0
0
0
0
12
% C
% Asp:
0
0
12
0
0
23
12
0
0
0
0
12
0
12
12
% D
% Glu:
0
23
0
12
23
0
12
12
0
23
12
23
12
0
12
% E
% Phe:
0
0
0
12
0
12
23
12
12
0
0
0
0
0
0
% F
% Gly:
0
0
12
0
12
23
0
0
12
0
0
0
0
0
0
% G
% His:
12
0
23
0
0
0
0
12
0
0
0
0
0
0
0
% H
% Ile:
23
0
0
0
12
0
12
12
0
12
12
0
0
0
0
% I
% Lys:
0
12
0
0
0
0
0
0
0
0
0
0
23
0
0
% K
% Leu:
0
0
12
23
0
0
0
0
23
0
12
12
0
12
12
% L
% Met:
0
0
0
0
12
0
0
0
0
0
12
0
0
0
12
% M
% Asn:
0
0
0
0
0
12
0
0
0
0
0
12
0
12
0
% N
% Pro:
34
12
12
34
12
0
12
0
0
23
12
23
12
23
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
12
0
12
0
0
0
% Q
% Arg:
0
0
0
0
0
0
12
0
12
12
12
0
0
12
12
% R
% Ser:
12
23
12
12
12
0
12
23
12
23
23
0
23
12
0
% S
% Thr:
12
12
23
0
12
12
0
23
12
0
0
0
12
12
12
% T
% Val:
0
12
0
12
12
0
0
0
12
0
12
12
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _