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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAP3K4 All Species: 16.06
Human Site: T971 Identified Species: 44.17
UniProt: Q9Y6R4 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6R4 NP_005913.2 1607 181552 T971 Q S I E G L M T L C Q E Q T S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851019 1604 181061 T972 Q S I E G L M T L R Q E Q T S
Cat Felis silvestris
Mouse Mus musculus O08648 1597 179930 T962 Q S I E G L M T V R H E Q T S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512333 716 80761 E106 V V S L S A W E E Q P V K I V
Chicken Gallus gallus XP_419617 1576 178289 S950 Q S I E G L I S L H Q E Q T S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689836 1475 168741 V865 V D N L L L V V M Q S A H L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_732373 1571 177332 T909 R E T Q S L L T V E R E R S I
Honey Bee Apis mellifera XP_392650 1209 140403 G599 I F V K S I A G N I I N G C E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797473 1747 197449 S996 E C A H L Q D S H S G G G A I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 93 N.A. 88.3 N.A. N.A. 38.9 84.5 N.A. 67 N.A. 25.2 29.6 N.A. 36.1
Protein Similarity: 100 N.A. N.A. 95.5 N.A. 92.4 N.A. N.A. 41.8 90.6 N.A. 78.2 N.A. 42 47.1 N.A. 53
P-Site Identity: 100 N.A. N.A. 93.3 N.A. 80 N.A. N.A. 0 80 N.A. 6.6 N.A. 20 0 N.A. 0
P-Site Similarity: 100 N.A. N.A. 93.3 N.A. 86.6 N.A. N.A. 6.6 93.3 N.A. 20 N.A. 66.6 20 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 0 12 12 0 0 0 0 12 0 12 0 % A
% Cys: 0 12 0 0 0 0 0 0 0 12 0 0 0 12 0 % C
% Asp: 0 12 0 0 0 0 12 0 0 0 0 0 0 0 0 % D
% Glu: 12 12 0 45 0 0 0 12 12 12 0 56 0 0 12 % E
% Phe: 0 12 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 45 0 0 12 0 0 12 12 23 0 0 % G
% His: 0 0 0 12 0 0 0 0 12 12 12 0 12 0 0 % H
% Ile: 12 0 45 0 0 12 12 0 0 12 12 0 0 12 23 % I
% Lys: 0 0 0 12 0 0 0 0 0 0 0 0 12 0 0 % K
% Leu: 0 0 0 23 23 67 12 0 34 0 0 0 0 12 0 % L
% Met: 0 0 0 0 0 0 34 0 12 0 0 0 0 0 0 % M
% Asn: 0 0 12 0 0 0 0 0 12 0 0 12 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % P
% Gln: 45 0 0 12 0 12 0 0 0 23 34 0 45 0 0 % Q
% Arg: 12 0 0 0 0 0 0 0 0 23 12 0 12 0 0 % R
% Ser: 0 45 12 0 34 0 0 23 0 12 12 0 0 12 45 % S
% Thr: 0 0 12 0 0 0 0 45 0 0 0 0 0 45 0 % T
% Val: 23 12 12 0 0 0 12 12 23 0 0 12 0 0 23 % V
% Trp: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _