KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K4
All Species:
13.03
Human Site:
Y850
Identified Species:
35.83
UniProt:
Q9Y6R4
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6R4
NP_005913.2
1607
181552
Y850
D
V
L
K
S
K
Q
Y
V
K
V
Q
I
P
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851019
1604
181061
Y851
D
V
L
K
S
K
Q
Y
V
K
V
Q
I
P
G
Cat
Felis silvestris
Mouse
Mus musculus
O08648
1597
179930
Y841
D
A
L
K
A
K
Q
Y
V
K
V
Q
I
P
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512333
716
80761
Chicken
Gallus gallus
XP_419617
1576
178289
Y829
N
A
L
K
T
K
E
Y
V
K
V
Q
I
P
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689836
1475
168741
F747
D
L
E
I
A
A
E
F
S
L
T
S
G
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732373
1571
177332
E787
A
L
V
E
N
E
A
E
L
G
S
Y
I
S
I
Honey Bee
Apis mellifera
XP_392650
1209
140403
F481
S
Y
R
A
A
F
V
F
L
S
R
V
P
L
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797473
1747
197449
H876
E
V
I
G
A
C
T
H
V
K
Q
Y
Y
H
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93
N.A.
88.3
N.A.
N.A.
38.9
84.5
N.A.
67
N.A.
25.2
29.6
N.A.
36.1
Protein Similarity:
100
N.A.
N.A.
95.5
N.A.
92.4
N.A.
N.A.
41.8
90.6
N.A.
78.2
N.A.
42
47.1
N.A.
53
P-Site Identity:
100
N.A.
N.A.
100
N.A.
86.6
N.A.
N.A.
0
73.3
N.A.
6.6
N.A.
6.6
0
N.A.
20
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
N.A.
N.A.
0
93.3
N.A.
33.3
N.A.
46.6
20
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
23
0
12
45
12
12
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% C
% Asp:
45
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% D
% Glu:
12
0
12
12
0
12
23
12
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
12
0
23
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
0
0
0
0
12
0
0
12
0
45
% G
% His:
0
0
0
0
0
0
0
12
0
0
0
0
0
12
0
% H
% Ile:
0
0
12
12
0
0
0
0
0
0
0
0
56
0
12
% I
% Lys:
0
0
0
45
0
45
0
0
0
56
0
0
0
0
0
% K
% Leu:
0
23
45
0
0
0
0
0
23
12
0
0
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
12
45
0
% P
% Gln:
0
0
0
0
0
0
34
0
0
0
12
45
0
0
0
% Q
% Arg:
0
0
12
0
0
0
0
0
0
0
12
0
0
0
0
% R
% Ser:
12
0
0
0
23
0
0
0
12
12
12
12
0
12
12
% S
% Thr:
0
0
0
0
12
0
12
0
0
0
12
0
0
0
0
% T
% Val:
0
34
12
0
0
0
12
0
56
0
45
12
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
0
0
45
0
0
0
23
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _