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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KL1
All Species:
2.73
Human Site:
S241
Identified Species:
6
UniProt:
Q9Y6S9
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6S9
NP_113652.1
549
60036
S241
H
S
R
H
S
G
L
S
S
G
S
T
Q
E
R
Chimpanzee
Pan troglodytes
XP_001158046
541
59251
M218
S
G
S
T
Q
E
R
M
K
A
Q
L
N
P
H
Rhesus Macaque
Macaca mulatta
XP_001095791
541
59146
R217
S
S
G
S
T
Q
E
R
M
K
A
Q
L
N
P
Dog
Lupus familis
XP_547909
601
65960
R297
H
P
Q
Q
P
G
L
R
S
G
S
T
P
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2S1
544
60175
N241
H
F
Q
Y
S
G
L
N
S
G
S
V
Q
E
K
Rat
Rattus norvegicus
Q63531
735
82865
R299
L
L
R
A
L
F
K
R
N
P
A
N
R
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511099
1074
119382
F430
N
R
S
P
E
E
S
F
D
H
P
H
V
K
R
Chicken
Gallus gallus
XP_421273
428
46446
G165
T
A
P
P
V
L
R
G
H
G
G
E
N
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697196
710
78963
D256
N
P
R
S
Y
C
E
D
V
G
C
Q
Q
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650697
681
77054
S284
L
N
G
A
K
Q
D
S
S
E
E
R
R
F
I
Honey Bee
Apis mellifera
XP_001119932
490
56604
T220
H
A
C
I
E
T
D
T
R
G
K
L
W
D
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.2
90.7
74
N.A.
78.6
20.5
N.A.
25.1
46.2
N.A.
27.3
N.A.
21
20.9
N.A.
N.A.
Protein Similarity:
100
93.4
91.9
77.3
N.A.
86.6
34.1
N.A.
35.6
56
N.A.
41.4
N.A.
38
40.6
N.A.
N.A.
P-Site Identity:
100
0
6.6
60
N.A.
60
6.6
N.A.
6.6
6.6
N.A.
20
N.A.
13.3
13.3
N.A.
N.A.
P-Site Similarity:
100
0
20
66.6
N.A.
86.6
26.6
N.A.
20
13.3
N.A.
26.6
N.A.
26.6
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
19
0
0
0
0
0
10
19
0
0
0
0
% A
% Cys:
0
0
10
0
0
10
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
19
10
10
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
19
19
19
0
0
10
10
10
0
28
10
% E
% Phe:
0
10
0
0
0
10
0
10
0
0
0
0
0
10
10
% F
% Gly:
0
10
19
0
0
28
0
10
0
55
10
0
0
0
19
% G
% His:
37
0
0
10
0
0
0
0
10
10
0
10
0
0
10
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
10
0
10
0
10
10
10
0
0
10
10
% K
% Leu:
19
10
0
0
10
10
28
0
0
0
0
19
10
10
0
% L
% Met:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% M
% Asn:
19
10
0
0
0
0
0
10
10
0
0
10
19
10
0
% N
% Pro:
0
19
10
19
10
0
0
0
0
10
10
0
10
10
10
% P
% Gln:
0
0
19
10
10
19
0
0
0
0
10
19
28
0
0
% Q
% Arg:
0
10
28
0
0
0
19
28
10
0
0
10
19
0
28
% R
% Ser:
19
19
19
19
19
0
10
19
37
0
28
0
0
10
0
% S
% Thr:
10
0
0
10
10
10
0
10
0
0
0
19
0
10
0
% T
% Val:
0
0
0
0
10
0
0
0
10
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _