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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DGKB All Species: 19.09
Human Site: S11 Identified Species: 42
UniProt: Q9Y6T7 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6T7 NP_004071.1 804 90595 S11 Q E K W A H L S P S E F S Q L
Chimpanzee Pan troglodytes XP_001148960 804 90603 S11 Q E K W A H L S P S E F S Q L
Rhesus Macaque Macaca mulatta XP_001105384 789 88608 T11 C I K S Q D S T K K L K D V L
Dog Lupus familis XP_539445 886 99592 I94 E Q H R R N Q I G C L R A A A
Cat Felis silvestris
Mouse Mus musculus Q6NS52 802 90253 S11 Q E K W A H L S P S E F S Q L
Rat Rattus norvegicus P49621 801 90269 S11 Q E K W A H L S P S E F S Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511802 697 78726
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q01583 1211 132942 S14 A P K W D K L S P R E F L Q L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q03603 812 91362 S12 P E Q F S R L S E Y A A Y S R
Sea Urchin Strong. purpuratus XP_001197889 1217 132437 A396 T L S W T N V A G S F F Y Q I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39017 728 79965 F10 D D G E L G M F F P S W T S K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 96.6 88.2 N.A. 96.5 96.1 N.A. 72.2 N.A. N.A. N.A. N.A. 34.9 N.A. 52 42.4
Protein Similarity: 100 99.8 97.5 89.5 N.A. 98.1 97.8 N.A. 78.2 N.A. N.A. N.A. N.A. 47.5 N.A. 66.1 52.6
P-Site Identity: 100 100 13.3 0 N.A. 100 100 N.A. 0 N.A. N.A. N.A. N.A. 60 N.A. 20 26.6
P-Site Similarity: 100 100 20 26.6 N.A. 100 100 N.A. 0 N.A. N.A. N.A. N.A. 60 N.A. 40 53.3
Percent
Protein Identity: N.A. N.A. N.A. 23.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 37 0 0 10 0 0 10 10 10 10 10 % A
% Cys: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 10 10 0 0 10 10 0 0 0 0 0 0 10 0 0 % D
% Glu: 10 46 0 10 0 0 0 0 10 0 46 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 10 10 0 10 55 0 0 0 % F
% Gly: 0 0 10 0 0 10 0 0 19 0 0 0 0 0 0 % G
% His: 0 0 10 0 0 37 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 10 % I
% Lys: 0 0 55 0 0 10 0 0 10 10 0 10 0 0 10 % K
% Leu: 0 10 0 0 10 0 55 0 0 0 19 0 10 0 55 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 10 0 0 0 0 0 0 46 10 0 0 0 0 0 % P
% Gln: 37 10 10 0 10 0 10 0 0 0 0 0 0 55 0 % Q
% Arg: 0 0 0 10 10 10 0 0 0 10 0 10 0 0 10 % R
% Ser: 0 0 10 10 10 0 10 55 0 46 10 0 37 19 0 % S
% Thr: 10 0 0 0 10 0 0 10 0 0 0 0 10 0 0 % T
% Val: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 55 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 0 19 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _