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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCIN All Species: 29.7
Human Site: S484 Identified Species: 65.33
UniProt: Q9Y6U3 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6U3 NP_001106177.1 715 80489 S484 K E P V H L L S L F K D K P L
Chimpanzee Pan troglodytes XP_527671 715 80462 S484 K E P V H L L S L F K D K P L
Rhesus Macaque Macaca mulatta XP_001082780 715 80424 S484 K E P I H L L S L F K D K P L
Dog Lupus familis XP_532479 731 81666 S500 K E P A H L L S L F K D K P L
Cat Felis silvestris
Mouse Mus musculus Q60604 715 80275 S484 K E P A H L L S L F K D K P L
Rat Rattus norvegicus Q68FP1 780 86049 S535 K E P A H L M S L F G G K P M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus O93510 778 85813 S533 K E P P H L M S M F G G K P L
Frog Xenopus laevis P14885 417 46006 T206 V R L F Q V R T S S S G F S R
Zebra Danio Brachydanio rerio NP_001038583 733 82084 S487 K E P P H L L S L F K D K P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q07171 798 88356 E547 V Q T N Q G H E P R H F Y K I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O81645 966 106448 A485 K E P P Q F V A L F Q H M V V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98 84.6 N.A. 91.1 55.6 N.A. N.A. 56.8 31.6 69.8 N.A. 33.7 N.A. N.A. N.A.
Protein Similarity: 100 99.8 99.3 89.3 N.A. 96.3 70.5 N.A. N.A. 72.7 42.7 83.7 N.A. 49.7 N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 93.3 66.6 N.A. N.A. 66.6 0 93.3 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 80 N.A. N.A. 80 13.3 93.3 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 33.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 28 0 0 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 55 0 0 0 % D
% Glu: 0 82 0 0 0 0 0 10 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 10 0 0 0 82 0 10 10 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 19 28 0 0 0 % G
% His: 0 0 0 0 73 0 10 0 0 0 10 10 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 82 0 0 0 0 0 0 0 0 0 55 0 73 10 0 % K
% Leu: 0 0 10 0 0 73 55 0 73 0 0 0 0 0 64 % L
% Met: 0 0 0 0 0 0 19 0 10 0 0 0 10 0 10 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 82 28 0 0 0 0 10 0 0 0 0 73 0 % P
% Gln: 0 10 0 0 28 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 10 0 0 0 0 10 0 0 10 0 0 0 0 10 % R
% Ser: 0 0 0 0 0 0 0 73 10 10 10 0 0 10 0 % S
% Thr: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % T
% Val: 19 0 0 19 0 10 10 0 0 0 0 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _