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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCIN All Species: 24.24
Human Site: Y416 Identified Species: 53.33
UniProt: Q9Y6U3 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6U3 NP_001106177.1 715 80489 Y416 I Q V D Q N S Y G E F Y G G D
Chimpanzee Pan troglodytes XP_527671 715 80462 Y416 I Q V D Q N S Y G E F Y G G D
Rhesus Macaque Macaca mulatta XP_001082780 715 80424 Y416 I Q V D Q N S Y G E F Y G G D
Dog Lupus familis XP_532479 731 81666 Y432 V E I D Q N S Y G E F Y G G D
Cat Felis silvestris
Mouse Mus musculus Q60604 715 80275 Y416 V Q I D P S S Y G E F Y G G D
Rat Rattus norvegicus Q68FP1 780 86049 Y467 P A T Y G Q F Y G G D S Y I I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus O93510 778 85813 Y465 P A T Y G Q F Y G G D S Y I I
Frog Xenopus laevis P14885 417 46006 E138 G D D S T K D E I T A S A I L
Zebra Danio Brachydanio rerio NP_001038583 733 82084 Y419 V P V D P E T Y G Q F Y G G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q07171 798 88356 V479 D E I V V S T V P F D E K L P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O81645 966 106448 S417 D H V G K L Y S G D C Y L V L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98 84.6 N.A. 91.1 55.6 N.A. N.A. 56.8 31.6 69.8 N.A. 33.7 N.A. N.A. N.A.
Protein Similarity: 100 99.8 99.3 89.3 N.A. 96.3 70.5 N.A. N.A. 72.7 42.7 83.7 N.A. 49.7 N.A. N.A. N.A.
P-Site Identity: 100 100 100 80 N.A. 73.3 13.3 N.A. N.A. 13.3 0 60 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 13.3 N.A. N.A. 13.3 0 80 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.1 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 0 0 0 0 0 0 0 0 10 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 19 10 10 55 0 0 10 0 0 10 28 0 0 0 55 % D
% Glu: 0 19 0 0 0 10 0 10 0 46 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 19 0 0 10 55 0 0 0 0 % F
% Gly: 10 0 0 10 19 0 0 0 82 19 0 0 55 55 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 28 0 28 0 0 0 0 0 10 0 0 0 0 28 19 % I
% Lys: 0 0 0 0 10 10 0 0 0 0 0 0 10 0 0 % K
% Leu: 0 0 0 0 0 10 0 0 0 0 0 0 10 10 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 37 0 0 0 0 0 0 0 0 0 % N
% Pro: 19 10 0 0 19 0 0 0 10 0 0 0 0 0 10 % P
% Gln: 0 37 0 0 37 19 0 0 0 10 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 10 0 19 46 10 0 0 0 28 0 0 0 % S
% Thr: 0 0 19 0 10 0 19 0 0 10 0 0 0 0 0 % T
% Val: 28 0 46 10 10 0 0 10 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 19 0 0 10 73 0 0 0 64 19 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _