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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX49
All Species:
8.79
Human Site:
S375
Identified Species:
14.87
UniProt:
Q9Y6V7
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6V7
NP_061943.2
483
54226
S375
K
K
K
L
E
E
F
S
V
E
E
A
E
V
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001115617
527
58467
S375
K
K
K
L
E
E
F
S
V
E
E
A
E
V
L
Dog
Lupus familis
XP_541930
488
54668
S375
K
K
Q
L
E
E
L
S
V
E
E
A
K
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q4FZF3
480
54076
V375
K
Q
Q
L
A
E
L
V
V
E
E
A
E
V
L
Rat
Rattus norvegicus
NP_001108495
480
54257
A375
K
Q
Q
L
A
E
L
A
V
E
E
A
Q
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026109
402
45009
R344
G
R
T
A
R
A
G
R
N
G
I
S
I
T
M
Frog
Xenopus laevis
NP_001085167
448
50232
P385
G
K
K
L
P
A
F
P
T
Q
E
E
E
V
M
Zebra Danio
Brachydanio rerio
NP_938179
468
53112
P375
Q
T
K
L
K
E
F
P
I
E
E
K
E
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07886
521
59659
P379
N
T
K
L
T
E
H
P
I
D
Q
R
M
V
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34580
489
54209
K410
G
K
K
L
D
E
Y
K
C
V
E
N
E
V
M
Sea Urchin
Strong. purpuratus
XP_781784
301
33445
I246
L
V
K
Q
K
T
R
I
A
S
L
A
M
F
K
Poplar Tree
Populus trichocarpa
XP_002311293
496
55653
E432
G
K
Q
F
E
K
F
E
C
K
E
N
E
V
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SA27
491
54817
N429
G
K
K
M
E
P
Y
N
K
K
V
I
T
D
S
Baker's Yeast
Sacchar. cerevisiae
P38719
431
47860
K376
I
E
D
R
I
N
K
K
M
T
E
T
N
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
84.8
94
N.A.
89.8
89
N.A.
N.A.
70.3
44.7
73.5
N.A.
45.4
N.A.
42.7
40.9
Protein Similarity:
100
N.A.
86.3
95.9
N.A.
94
94
N.A.
N.A.
76.4
59.8
87.1
N.A.
63.9
N.A.
59.7
52.8
P-Site Identity:
100
N.A.
100
80
N.A.
66.6
60
N.A.
N.A.
0
46.6
60
N.A.
26.6
N.A.
46.6
13.3
P-Site Similarity:
100
N.A.
100
93.3
N.A.
80
86.6
N.A.
N.A.
20
60
80
N.A.
46.6
N.A.
66.6
20
Percent
Protein Identity:
42.5
N.A.
N.A.
43.3
43.4
N.A.
Protein Similarity:
62.3
N.A.
N.A.
62.9
59.8
N.A.
P-Site Identity:
46.6
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
46.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
15
15
0
8
8
0
0
43
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
0
0
0
8
0
0
0
8
0
% D
% Glu:
0
8
0
0
36
58
0
8
0
43
72
8
50
0
8
% E
% Phe:
0
0
0
8
0
0
36
0
0
0
0
0
0
8
0
% F
% Gly:
36
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
0
0
8
15
0
8
8
8
0
0
% I
% Lys:
36
50
58
0
15
8
8
15
8
15
0
8
8
8
8
% K
% Leu:
8
0
0
65
0
0
22
0
0
0
8
0
0
0
50
% L
% Met:
0
0
0
8
0
0
0
0
8
0
0
0
15
0
22
% M
% Asn:
8
0
0
0
0
8
0
8
8
0
0
15
8
0
0
% N
% Pro:
0
0
0
0
8
8
0
22
0
0
0
0
0
0
0
% P
% Gln:
8
15
29
8
0
0
0
0
0
8
8
0
8
0
0
% Q
% Arg:
0
8
0
8
8
0
8
8
0
0
0
8
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
22
0
8
0
8
0
0
8
% S
% Thr:
0
15
8
0
8
8
0
0
8
8
0
8
8
8
0
% T
% Val:
0
8
0
0
0
0
0
8
36
8
8
0
0
72
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _