KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUSP10
All Species:
18.18
Human Site:
S258
Identified Species:
36.36
UniProt:
Q9Y6W6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6W6
NP_009138.1
482
52642
S258
P
L
H
I
V
L
E
S
L
K
R
E
G
K
E
Chimpanzee
Pan troglodytes
XP_001172978
482
52611
S258
P
L
H
I
V
L
E
S
L
K
R
E
G
K
E
Rhesus Macaque
Macaca mulatta
XP_001101558
482
52598
S258
P
L
H
I
V
L
E
S
L
K
R
E
G
K
E
Dog
Lupus familis
XP_849569
487
52932
S258
P
L
H
I
V
L
E
S
L
K
R
E
G
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESS0
483
52512
S259
P
L
H
I
V
L
E
S
L
K
R
E
G
K
E
Rat
Rattus norvegicus
Q64346
381
42300
E181
S
D
S
S
S
D
I
E
S
D
L
D
R
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512790
480
52472
R258
V
V
L
E
S
L
K
R
E
G
K
E
P
L
V
Chicken
Gallus gallus
NP_001026215
478
51814
G258
L
E
S
L
K
R
E
G
K
E
P
L
V
L
K
Frog
Xenopus laevis
NP_001083256
378
42018
E178
S
D
S
S
S
D
I
E
S
D
I
D
R
D
P
Zebra Danio
Brachydanio rerio
XP_001919447
210
23610
A10
S
G
F
R
Q
T
H
A
D
L
C
E
H
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392375
608
66068
A361
P
L
F
L
V
L
V
A
L
L
D
D
N
R
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789413
532
58126
V275
N
H
P
T
S
L
V
V
S
A
L
K
K
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.1
95.2
N.A.
96
27.7
N.A.
91
88.3
27.5
35.6
N.A.
N.A.
31.7
N.A.
31
Protein Similarity:
100
99.7
99.3
96.9
N.A.
97.7
43.9
N.A.
94.6
91.2
43.5
40
N.A.
N.A.
49.6
N.A.
50.9
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
13.3
6.6
0
6.6
N.A.
N.A.
40
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
33.3
26.6
6.6
13.3
N.A.
N.A.
66.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
17
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
17
0
0
0
17
0
0
9
17
9
25
0
17
0
% D
% Glu:
0
9
0
9
0
0
50
17
9
9
0
59
0
9
50
% E
% Phe:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
9
0
9
0
0
42
0
9
% G
% His:
0
9
42
0
0
0
9
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
42
0
0
17
0
0
0
9
0
0
0
0
% I
% Lys:
0
0
0
0
9
0
9
0
9
42
9
9
9
42
9
% K
% Leu:
9
50
9
17
0
67
0
0
50
17
17
9
0
17
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
50
0
9
0
0
0
0
0
0
0
9
0
9
0
17
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
9
0
9
0
0
42
0
17
9
0
% R
% Ser:
25
0
25
17
34
0
0
42
25
0
0
0
0
9
0
% S
% Thr:
0
0
0
9
0
9
0
0
0
0
0
0
0
0
0
% T
% Val:
9
9
0
0
50
0
17
9
0
0
0
0
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _