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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS3
All Species:
16.97
Human Site:
S431
Identified Species:
31.11
UniProt:
Q9Y6X2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6X2
NP_006090.2
628
68017
S431
G
L
D
G
L
Q
Y
S
P
V
Q
G
G
D
P
Chimpanzee
Pan troglodytes
XP_523109
766
83908
T554
V
D
G
C
L
S
S
T
L
E
H
Q
V
A
S
Rhesus Macaque
Macaca mulatta
XP_001095153
700
75283
S503
G
L
D
G
L
Q
Y
S
P
V
Q
E
G
N
P
Dog
Lupus familis
XP_540278
628
68106
S431
G
L
D
G
L
Q
Y
S
P
V
Q
E
G
N
P
Cat
Felis silvestris
Mouse
Mus musculus
O54714
628
68299
S431
G
L
D
G
L
Q
Y
S
A
V
Q
E
G
I
Q
Rat
Rattus norvegicus
O70260
628
68345
S431
G
L
D
G
L
Q
Y
S
P
V
Q
E
G
N
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516107
756
82793
S538
V
D
G
C
L
S
S
S
L
D
H
Q
V
S
S
Chicken
Gallus gallus
NP_001026627
564
62782
V373
N
E
K
K
P
T
W
V
C
P
V
C
D
K
K
Frog
Xenopus laevis
NP_001086078
633
69985
I438
G
G
I
E
A
S
S
I
Y
S
M
T
P
E
L
Zebra Danio
Brachydanio rerio
XP_688159
659
71801
V439
V
E
D
S
C
R
S
V
L
S
D
H
R
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
G532
V
V
P
A
T
V
N
G
T
A
S
C
S
S
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
P467
E
L
S
Q
W
H
A
P
D
G
S
L
C
P
S
Baker's Yeast
Sacchar. cerevisiae
Q12216
726
81160
Q442
H
S
V
K
N
E
N
Q
G
T
V
K
Q
E
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.5
88.7
97.2
N.A.
96.9
96.6
N.A.
51.7
57.7
71.2
57.2
N.A.
N.A.
N.A.
22.9
N.A.
Protein Similarity:
100
60.9
89
97.7
N.A.
98
97.7
N.A.
61.9
68.7
81.1
68.2
N.A.
N.A.
N.A.
37.9
N.A.
P-Site Identity:
100
6.6
86.6
86.6
N.A.
73.3
80
N.A.
13.3
0
6.6
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
13.3
93.3
93.3
N.A.
73.3
86.6
N.A.
13.3
6.6
13.3
20
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
20.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.2
36.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
8
0
8
8
0
0
0
8
0
% A
% Cys:
0
0
0
16
8
0
0
0
8
0
0
16
8
0
0
% C
% Asp:
0
16
47
0
0
0
0
0
8
8
8
0
8
8
0
% D
% Glu:
8
16
0
8
0
8
0
0
0
8
0
31
0
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
47
8
16
39
0
0
0
8
8
8
0
8
39
0
0
% G
% His:
8
0
0
0
0
8
0
0
0
0
16
8
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
8
0
0
0
0
0
8
0
% I
% Lys:
0
0
8
16
0
0
0
0
0
0
0
8
0
8
8
% K
% Leu:
0
47
0
0
54
0
0
0
24
0
0
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
16
0
0
0
0
0
0
31
0
% N
% Pro:
0
0
8
0
8
0
0
8
31
8
0
0
8
8
24
% P
% Gln:
0
0
0
8
0
39
0
8
0
0
39
16
8
0
24
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
8
8
8
0
24
31
47
0
16
16
0
8
16
31
% S
% Thr:
0
0
0
0
8
8
0
8
8
8
0
8
0
0
8
% T
% Val:
31
8
8
0
0
8
0
16
0
39
16
0
16
0
0
% V
% Trp:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
39
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _