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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS3
All Species:
13.64
Human Site:
S439
Identified Species:
25
UniProt:
Q9Y6X2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6X2
NP_006090.2
628
68017
S439
P
V
Q
G
G
D
P
S
E
N
K
K
K
V
E
Chimpanzee
Pan troglodytes
XP_523109
766
83908
H562
L
E
H
Q
V
A
S
H
H
Q
S
S
N
K
N
Rhesus Macaque
Macaca mulatta
XP_001095153
700
75283
S511
P
V
Q
E
G
N
P
S
E
N
K
K
K
V
E
Dog
Lupus familis
XP_540278
628
68106
S439
P
V
Q
E
G
N
P
S
E
N
K
K
K
V
E
Cat
Felis silvestris
Mouse
Mus musculus
O54714
628
68299
P439
A
V
Q
E
G
I
Q
P
E
S
K
K
R
V
E
Rat
Rattus norvegicus
O70260
628
68345
S439
P
V
Q
E
G
N
Q
S
E
N
K
K
R
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516107
756
82793
H546
L
D
H
Q
V
S
S
H
Q
Q
S
S
N
K
N
Chicken
Gallus gallus
NP_001026627
564
62782
A381
C
P
V
C
D
K
K
A
P
Y
E
H
L
I
I
Frog
Xenopus laevis
NP_001086078
633
69985
K446
Y
S
M
T
P
E
L
K
H
N
P
E
T
K
K
Zebra Danio
Brachydanio rerio
XP_688159
659
71801
S447
L
S
D
H
R
N
S
S
S
H
S
S
S
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
N540
T
A
S
C
S
S
T
N
G
N
G
L
A
N
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
A475
D
G
S
L
C
P
S
A
V
D
I
K
R
K
M
Baker's Yeast
Sacchar. cerevisiae
Q12216
726
81160
D450
G
T
V
K
Q
E
Q
D
Y
D
S
R
N
A
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.5
88.7
97.2
N.A.
96.9
96.6
N.A.
51.7
57.7
71.2
57.2
N.A.
N.A.
N.A.
22.9
N.A.
Protein Similarity:
100
60.9
89
97.7
N.A.
98
97.7
N.A.
61.9
68.7
81.1
68.2
N.A.
N.A.
N.A.
37.9
N.A.
P-Site Identity:
100
0
86.6
86.6
N.A.
53.3
73.3
N.A.
0
0
6.6
6.6
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
0
93.3
93.3
N.A.
66.6
86.6
N.A.
6.6
20
26.6
26.6
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
20.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.2
36.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
8
0
16
0
0
0
0
8
8
0
% A
% Cys:
8
0
0
16
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
0
8
8
0
8
0
16
0
0
0
0
0
% D
% Glu:
0
8
0
31
0
16
0
0
39
0
8
8
0
0
47
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
8
8
0
8
39
0
0
0
8
0
8
0
0
0
0
% G
% His:
0
0
16
8
0
0
0
16
16
8
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
8
0
0
8
8
% I
% Lys:
0
0
0
8
0
8
8
8
0
0
39
47
24
31
16
% K
% Leu:
24
0
0
8
0
0
8
0
0
0
0
8
8
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
31
0
8
0
47
0
0
24
8
16
% N
% Pro:
31
8
0
0
8
8
24
8
8
0
8
0
0
0
0
% P
% Gln:
0
0
39
16
8
0
24
0
8
16
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
8
24
0
0
% R
% Ser:
0
16
16
0
8
16
31
39
8
8
31
24
8
8
0
% S
% Thr:
8
8
0
8
0
0
8
0
0
0
0
0
8
0
0
% T
% Val:
0
39
16
0
16
0
0
0
8
0
0
0
0
39
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _