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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS3
All Species:
23.64
Human Site:
S454
Identified Species:
43.33
UniProt:
Q9Y6X2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6X2
NP_006090.2
628
68017
S454
V
I
D
L
T
I
E
S
S
S
D
E
E
D
L
Chimpanzee
Pan troglodytes
XP_523109
766
83908
L577
K
K
V
E
V
I
D
L
T
I
D
S
S
S
D
Rhesus Macaque
Macaca mulatta
XP_001095153
700
75283
S526
V
I
D
L
T
I
E
S
S
S
D
E
E
D
L
Dog
Lupus familis
XP_540278
628
68106
S454
V
I
D
L
T
I
E
S
S
S
D
E
E
D
L
Cat
Felis silvestris
Mouse
Mus musculus
O54714
628
68299
S454
V
I
D
L
T
I
E
S
S
S
D
E
E
D
L
Rat
Rattus norvegicus
O70260
628
68345
S454
V
I
D
L
T
I
E
S
S
S
D
E
E
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516107
756
82793
L561
K
K
V
E
V
I
D
L
T
I
D
S
S
S
E
Chicken
Gallus gallus
NP_001026627
564
62782
L396
D
G
L
F
M
E
I
L
K
Y
C
T
D
C
D
Frog
Xenopus laevis
NP_001086078
633
69985
T461
K
V
E
V
I
D
L
T
L
D
S
S
S
D
D
Zebra Danio
Brachydanio rerio
XP_688159
659
71801
T462
K
V
E
V
I
D
L
T
L
D
S
S
S
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
D555
A
A
K
K
K
P
A
D
D
D
I
I
T
L
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
E490
E
M
L
P
V
K
Q
E
G
Y
S
D
G
P
A
Baker's Yeast
Sacchar. cerevisiae
Q12216
726
81160
S465
D
T
N
L
R
N
G
S
N
H
N
E
P
E
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.5
88.7
97.2
N.A.
96.9
96.6
N.A.
51.7
57.7
71.2
57.2
N.A.
N.A.
N.A.
22.9
N.A.
Protein Similarity:
100
60.9
89
97.7
N.A.
98
97.7
N.A.
61.9
68.7
81.1
68.2
N.A.
N.A.
N.A.
37.9
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
13.3
0
6.6
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
26.6
6.6
33.3
33.3
N.A.
N.A.
N.A.
0
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
20.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.2
36.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
8
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% C
% Asp:
16
0
39
0
0
16
16
8
8
24
54
8
8
54
24
% D
% Glu:
8
0
16
16
0
8
39
8
0
0
0
47
39
8
16
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
8
0
8
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
39
0
0
16
54
8
0
0
16
8
8
0
0
8
% I
% Lys:
31
16
8
8
8
8
0
0
8
0
0
0
0
0
0
% K
% Leu:
0
0
16
47
0
0
16
24
16
0
0
0
0
8
39
% L
% Met:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
0
8
0
8
0
0
0
0
% N
% Pro:
0
0
0
8
0
8
0
0
0
0
0
0
8
8
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
47
39
39
24
31
31
16
8
% S
% Thr:
0
8
0
0
39
0
0
16
16
0
0
8
8
0
0
% T
% Val:
39
16
16
16
24
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _