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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIAS3 All Species: 20.61
Human Site: S510 Identified Species: 37.78
UniProt: Q9Y6X2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6X2 NP_006090.2 628 68017 S510 L G G D F L S S L P L H E Y P
Chimpanzee Pan troglodytes XP_523109 766 83908 Y633 L P A V D T S Y I N T S L I Q
Rhesus Macaque Macaca mulatta XP_001095153 700 75283 S582 L G G D F L S S L P L H E Y P
Dog Lupus familis XP_540278 628 68106 S510 L G G D F L S S L P L H E Y P
Cat Felis silvestris
Mouse Mus musculus O54714 628 68299 S510 L G S D F L S S L P L H E Y P
Rat Rattus norvegicus O70260 628 68345 S510 L G S D F L S S L P L H E Y P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516107 756 82793 D617 T P S L P A V D P S Y I N T S
Chicken Gallus gallus NP_001026627 564 62782 K452 S S H Q Q S N K N K K V E V I
Frog Xenopus laevis NP_001086078 633 69985 L517 A T I S S D Y L S S L P L P D
Zebra Danio Brachydanio rerio XP_688159 659 71801 Y518 M P A M E T N Y I P P P P P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q94361 793 89556 E611 K T K D D D I E I I T L D D T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q680Q4 884 97015 G546 P M S S S A T G S G R D G D D
Baker's Yeast Sacchar. cerevisiae Q12216 726 81160 T521 S D Y N P N H T S T P K G S P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 50.5 88.7 97.2 N.A. 96.9 96.6 N.A. 51.7 57.7 71.2 57.2 N.A. N.A. N.A. 22.9 N.A.
Protein Similarity: 100 60.9 89 97.7 N.A. 98 97.7 N.A. 61.9 68.7 81.1 68.2 N.A. N.A. N.A. 37.9 N.A.
P-Site Identity: 100 13.3 100 100 N.A. 93.3 93.3 N.A. 0 6.6 6.6 6.6 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 20 100 100 N.A. 93.3 93.3 N.A. 0 13.3 6.6 26.6 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.9 20.3 N.A.
Protein Similarity: N.A. N.A. N.A. 33.2 36.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 16 0 0 16 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 47 16 16 0 8 0 0 0 8 8 16 16 % D
% Glu: 0 0 0 0 8 0 0 8 0 0 0 0 47 0 0 % E
% Phe: 0 0 0 0 39 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 39 24 0 0 0 0 8 0 8 0 0 16 0 0 % G
% His: 0 0 8 0 0 0 8 0 0 0 0 39 0 0 0 % H
% Ile: 0 0 8 0 0 0 8 0 24 8 0 8 0 8 8 % I
% Lys: 8 0 8 0 0 0 0 8 0 8 8 8 0 0 0 % K
% Leu: 47 0 0 8 0 39 0 8 39 0 47 8 16 0 8 % L
% Met: 8 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 8 16 0 8 8 0 0 8 0 0 % N
% Pro: 8 24 0 0 16 0 0 0 8 47 16 16 8 16 47 % P
% Gln: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 16 8 31 16 16 8 47 39 24 16 0 8 0 8 8 % S
% Thr: 8 16 0 0 0 16 8 8 0 8 16 0 0 8 8 % T
% Val: 0 0 0 8 0 0 8 0 0 0 0 8 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 8 16 0 0 8 0 0 39 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _