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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIAS3 All Species: 19.39
Human Site: T69 Identified Species: 35.56
UniProt: Q9Y6X2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y6X2 NP_006090.2 628 68017 T69 R R R F P R K T L G P S D L S
Chimpanzee Pan troglodytes XP_523109 766 83908 I184 R R R F P Q K I M T P A D L S
Rhesus Macaque Macaca mulatta XP_001095153 700 75283 T141 R R R F P R K T L G P S D L S
Dog Lupus familis XP_540278 628 68106 T69 R R R F P R K T L G P S D L S
Cat Felis silvestris
Mouse Mus musculus O54714 628 68299 T69 R R R F P R K T L G P S D L S
Rat Rattus norvegicus O70260 628 68345 T69 R R R F P R K T L G P S D L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516107 756 82793 I168 R R R F P Q K I M T P A D L S
Chicken Gallus gallus NP_001026627 564 62782 G24 S E L Q V L L G Y A G R N K H
Frog Xenopus laevis NP_001086078 633 69985 G74 S M L H M P G G A L P S A N S
Zebra Danio Brachydanio rerio XP_688159 659 71801 M69 R R R F P T K M V S P T D L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q94361 793 89556 H141 Q Q Q Q P Q P H N L L H Q Q M
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q680Q4 884 97015 T72 V A K L V D D T Y R K M Q V S
Baker's Yeast Sacchar. cerevisiae Q12216 726 81160 H85 R K S C D I G H I D P W R P K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 50.5 88.7 97.2 N.A. 96.9 96.6 N.A. 51.7 57.7 71.2 57.2 N.A. N.A. N.A. 22.9 N.A.
Protein Similarity: 100 60.9 89 97.7 N.A. 98 97.7 N.A. 61.9 68.7 81.1 68.2 N.A. N.A. N.A. 37.9 N.A.
P-Site Identity: 100 66.6 100 100 N.A. 100 100 N.A. 66.6 0 20 66.6 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 86.6 100 100 N.A. 100 100 N.A. 86.6 6.6 20 80 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.9 20.3 N.A.
Protein Similarity: N.A. N.A. N.A. 33.2 36.3 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 8 8 0 16 8 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 8 8 0 0 8 0 0 62 0 0 % D
% Glu: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 62 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 16 16 0 39 8 0 0 0 0 % G
% His: 0 0 0 8 0 0 0 16 0 0 0 8 0 0 8 % H
% Ile: 0 0 0 0 0 8 0 16 8 0 0 0 0 0 0 % I
% Lys: 0 8 8 0 0 0 62 0 0 0 8 0 0 8 8 % K
% Leu: 0 0 16 8 0 8 8 0 39 16 8 0 0 62 0 % L
% Met: 0 8 0 0 8 0 0 8 16 0 0 8 0 0 8 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 0 8 8 0 % N
% Pro: 0 0 0 0 70 8 8 0 0 0 77 0 0 8 0 % P
% Gln: 8 8 8 16 0 24 0 0 0 0 0 0 16 8 0 % Q
% Arg: 70 62 62 0 0 39 0 0 0 8 0 8 8 0 0 % R
% Ser: 16 0 8 0 0 0 0 0 0 8 0 47 0 0 77 % S
% Thr: 0 0 0 0 0 8 0 47 0 16 0 8 0 0 0 % T
% Val: 8 0 0 0 16 0 0 0 8 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 16 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _