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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS3
All Species:
24.55
Human Site:
Y186
Identified Species:
45
UniProt:
Q9Y6X2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6X2
NP_006090.2
628
68017
Y186
L
P
G
A
K
C
D
Y
T
I
Q
V
Q
L
R
Chimpanzee
Pan troglodytes
XP_523109
766
83908
T310
S
G
T
K
C
D
F
T
V
Q
V
Q
L
R
F
Rhesus Macaque
Macaca mulatta
XP_001095153
700
75283
Y258
L
P
G
A
K
C
D
Y
T
I
Q
V
Q
L
R
Dog
Lupus familis
XP_540278
628
68106
Y186
L
P
G
A
K
C
D
Y
T
I
Q
V
Q
L
R
Cat
Felis silvestris
Mouse
Mus musculus
O54714
628
68299
Y186
L
P
G
A
K
C
D
Y
T
I
Q
V
Q
L
R
Rat
Rattus norvegicus
O70260
628
68345
Y186
L
P
G
A
K
C
D
Y
T
I
Q
V
Q
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516107
756
82793
T294
S
G
T
K
C
D
F
T
V
Q
V
Q
L
R
F
Chicken
Gallus gallus
NP_001026627
564
62782
H133
T
S
A
L
H
P
V
H
P
D
I
K
L
Q
K
Frog
Xenopus laevis
NP_001086078
633
69985
Y193
L
P
G
A
K
C
D
Y
T
V
Q
V
Q
L
R
Zebra Danio
Brachydanio rerio
XP_688159
659
71801
T195
S
G
T
K
C
D
F
T
V
Q
V
Q
L
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
L290
T
P
L
P
R
Y
E
L
Q
L
R
F
F
N
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
Y221
D
L
L
A
K
P
E
Y
D
V
Q
A
W
C
M
Baker's Yeast
Sacchar. cerevisiae
Q12216
726
81160
K196
K
S
N
H
D
L
L
K
S
N
K
S
Y
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.5
88.7
97.2
N.A.
96.9
96.6
N.A.
51.7
57.7
71.2
57.2
N.A.
N.A.
N.A.
22.9
N.A.
Protein Similarity:
100
60.9
89
97.7
N.A.
98
97.7
N.A.
61.9
68.7
81.1
68.2
N.A.
N.A.
N.A.
37.9
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
0
0
93.3
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
0
13.3
100
0
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
20.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.2
36.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
54
0
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
24
47
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
0
0
0
8
24
47
0
8
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
16
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
24
0
0
0
0
8
8
0
24
% F
% Gly:
0
24
47
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
8
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
39
8
0
0
0
0
% I
% Lys:
8
0
0
24
54
0
0
8
0
0
8
8
0
8
8
% K
% Leu:
47
8
16
8
0
8
8
8
0
8
0
0
31
47
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
0
0
0
0
8
0
0
0
8
0
% N
% Pro:
0
54
0
8
0
16
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
24
54
24
47
8
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
8
0
0
24
47
% R
% Ser:
24
16
0
0
0
0
0
0
8
0
0
8
0
0
0
% S
% Thr:
16
0
24
0
0
0
0
24
47
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
8
0
24
16
24
47
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
8
0
54
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _