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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS3
All Species:
22.73
Human Site:
Y206
Identified Species:
41.67
UniProt:
Q9Y6X2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6X2
NP_006090.2
628
68017
Y206
T
S
C
P
Q
E
D
Y
F
P
P
N
L
F
V
Chimpanzee
Pan troglodytes
XP_523109
766
83908
F330
S
C
P
Q
E
D
H
F
P
P
N
L
C
V
K
Rhesus Macaque
Macaca mulatta
XP_001095153
700
75283
Y278
T
S
C
P
Q
E
D
Y
F
P
P
N
L
F
V
Dog
Lupus familis
XP_540278
628
68106
Y206
T
S
C
P
Q
E
D
Y
F
P
P
N
L
F
V
Cat
Felis silvestris
Mouse
Mus musculus
O54714
628
68299
Y206
T
S
C
P
Q
E
D
Y
F
P
P
N
L
F
V
Rat
Rattus norvegicus
O70260
628
68345
Y206
T
S
C
P
Q
E
D
Y
F
P
P
N
L
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516107
756
82793
F314
S
C
P
Q
E
D
H
F
P
P
N
L
C
V
K
Chicken
Gallus gallus
NP_001026627
564
62782
P153
L
L
D
E
L
I
K
P
T
S
L
A
S
D
N
Frog
Xenopus laevis
NP_001086078
633
69985
Y213
T
S
C
P
Q
E
D
Y
F
P
P
N
L
F
V
Zebra Danio
Brachydanio rerio
XP_688159
659
71801
F215
S
C
P
Q
E
D
H
F
P
P
N
L
C
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
P310
G
P
Q
K
D
D
F
P
L
N
C
Y
A
R
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
P241
V
L
F
R
M
Q
W
P
Q
Y
A
D
L
Q
V
Baker's Yeast
Sacchar. cerevisiae
Q12216
726
81160
E216
F
S
I
P
F
I
Y
E
T
V
G
H
E
A
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.5
88.7
97.2
N.A.
96.9
96.6
N.A.
51.7
57.7
71.2
57.2
N.A.
N.A.
N.A.
22.9
N.A.
Protein Similarity:
100
60.9
89
97.7
N.A.
98
97.7
N.A.
61.9
68.7
81.1
68.2
N.A.
N.A.
N.A.
37.9
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
6.6
0
100
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
33.3
0
100
33.3
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
20.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.2
36.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
8
8
8
0
% A
% Cys:
0
24
47
0
0
0
0
0
0
0
8
0
24
0
0
% C
% Asp:
0
0
8
0
8
31
47
0
0
0
0
8
0
8
0
% D
% Glu:
0
0
0
8
24
47
0
8
0
0
0
0
8
0
0
% E
% Phe:
8
0
8
0
8
0
8
24
47
0
0
0
0
47
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
24
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
8
0
0
16
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
24
% K
% Leu:
8
16
0
0
8
0
0
0
8
0
8
24
54
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
24
47
0
0
8
% N
% Pro:
0
8
24
54
0
0
0
24
24
70
47
0
0
0
0
% P
% Gln:
0
0
8
24
47
8
0
0
8
0
0
0
0
8
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
24
54
0
0
0
0
0
0
0
8
0
0
8
0
0
% S
% Thr:
47
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
0
8
0
0
0
24
62
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
47
0
8
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _