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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS3
All Species:
36.06
Human Site:
Y270
Identified Species:
66.11
UniProt:
Q9Y6X2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6X2
NP_006090.2
628
68017
Y270
S
S
E
F
G
R
N
Y
S
L
S
V
Y
L
V
Chimpanzee
Pan troglodytes
XP_523109
766
83908
Y393
T
A
E
I
G
R
N
Y
S
M
A
V
Y
L
V
Rhesus Macaque
Macaca mulatta
XP_001095153
700
75283
Y342
S
S
E
F
G
R
N
Y
S
L
S
V
Y
L
V
Dog
Lupus familis
XP_540278
628
68106
Y270
S
S
E
F
G
R
N
Y
S
L
S
V
Y
L
V
Cat
Felis silvestris
Mouse
Mus musculus
O54714
628
68299
Y270
S
S
E
F
G
R
N
Y
S
L
S
V
Y
L
V
Rat
Rattus norvegicus
O70260
628
68345
Y270
S
S
E
F
G
R
N
Y
S
L
S
V
Y
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516107
756
82793
Y377
T
A
E
I
G
R
N
Y
S
M
A
V
Y
L
V
Chicken
Gallus gallus
NP_001026627
564
62782
D213
E
T
S
C
P
Q
E
D
H
F
P
P
N
L
C
Frog
Xenopus laevis
NP_001086078
633
69985
Y277
S
S
E
F
G
R
N
Y
S
L
S
V
Y
L
V
Zebra Danio
Brachydanio rerio
XP_688159
659
71801
Y278
T
S
E
I
G
R
S
Y
S
M
A
V
Y
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
A372
A
D
K
R
V
W
A
A
G
V
Y
F
V
H
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
R306
G
V
R
L
V
K
R
R
T
L
Q
Q
V
L
N
Baker's Yeast
Sacchar. cerevisiae
Q12216
726
81160
S282
L
N
I
D
K
E
Y
S
I
S
C
F
I
V
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.5
88.7
97.2
N.A.
96.9
96.6
N.A.
51.7
57.7
71.2
57.2
N.A.
N.A.
N.A.
22.9
N.A.
Protein Similarity:
100
60.9
89
97.7
N.A.
98
97.7
N.A.
61.9
68.7
81.1
68.2
N.A.
N.A.
N.A.
37.9
N.A.
P-Site Identity:
100
66.6
100
100
N.A.
100
100
N.A.
66.6
6.6
100
66.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
93.3
20
100
93.3
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
20.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.2
36.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
0
0
0
0
8
8
0
0
24
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
8
% C
% Asp:
0
8
0
8
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
8
0
70
0
0
8
8
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
47
0
0
0
0
0
8
0
16
0
0
0
% F
% Gly:
8
0
0
0
70
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% H
% Ile:
0
0
8
24
0
0
0
0
8
0
0
0
8
0
0
% I
% Lys:
0
0
8
0
8
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
8
0
0
0
0
0
54
0
0
0
85
0
% L
% Met:
0
0
0
0
0
0
0
0
0
24
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
62
0
0
0
0
0
8
0
8
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
8
8
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
8
8
0
0
0
% Q
% Arg:
0
0
8
8
0
70
8
8
0
0
0
0
0
0
8
% R
% Ser:
47
54
8
0
0
0
8
8
70
8
47
0
0
0
0
% S
% Thr:
24
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% T
% Val:
0
8
0
0
16
0
0
0
0
8
0
70
16
8
70
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
70
0
0
8
0
70
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _