KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS3
All Species:
37.27
Human Site:
Y354
Identified Species:
68.33
UniProt:
Q9Y6X2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6X2
NP_006090.2
628
68017
Y354
Q
S
F
D
A
A
L
Y
L
Q
M
N
E
K
K
Chimpanzee
Pan troglodytes
XP_523109
766
83908
Y477
Q
C
F
D
A
T
L
Y
I
Q
M
N
E
K
K
Rhesus Macaque
Macaca mulatta
XP_001095153
700
75283
Y426
Q
S
F
D
A
A
L
Y
L
Q
M
N
E
K
K
Dog
Lupus familis
XP_540278
628
68106
Y354
Q
S
F
D
A
A
L
Y
L
Q
M
N
E
K
K
Cat
Felis silvestris
Mouse
Mus musculus
O54714
628
68299
Y354
Q
S
F
D
A
A
L
Y
L
Q
M
N
E
K
K
Rat
Rattus norvegicus
O70260
628
68345
Y354
Q
S
F
D
A
A
L
Y
L
Q
M
N
E
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516107
756
82793
Y461
Q
C
F
D
A
T
L
Y
I
Q
M
N
E
K
K
Chicken
Gallus gallus
NP_001026627
564
62782
R296
S
S
T
V
L
L
Q
R
L
R
A
K
G
I
R
Frog
Xenopus laevis
NP_001086078
633
69985
Y361
Q
C
F
D
A
A
L
Y
L
Q
M
N
E
K
K
Zebra Danio
Brachydanio rerio
XP_688159
659
71801
Y362
Q
C
F
D
A
T
L
Y
I
Q
M
N
E
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
Y455
Q
C
F
D
L
L
S
Y
L
M
M
N
E
K
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
F390
G
C
F
D
L
D
V
F
V
E
L
N
Q
R
S
Baker's Yeast
Sacchar. cerevisiae
Q12216
726
81160
F365
Q
C
F
D
A
L
W
F
L
H
S
Q
S
Q
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.5
88.7
97.2
N.A.
96.9
96.6
N.A.
51.7
57.7
71.2
57.2
N.A.
N.A.
N.A.
22.9
N.A.
Protein Similarity:
100
60.9
89
97.7
N.A.
98
97.7
N.A.
61.9
68.7
81.1
68.2
N.A.
N.A.
N.A.
37.9
N.A.
P-Site Identity:
100
80
100
100
N.A.
100
100
N.A.
80
13.3
93.3
80
N.A.
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
100
86.6
100
100
N.A.
100
100
N.A.
86.6
26.6
93.3
86.6
N.A.
N.A.
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
20.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.2
36.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
77
47
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
54
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
93
0
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
8
0
0
77
0
0
% E
% Phe:
0
0
93
0
0
0
0
16
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
24
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
8
0
77
77
% K
% Leu:
0
0
0
0
24
24
70
0
70
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
77
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
85
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
85
0
0
0
0
0
8
0
0
70
0
8
8
8
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
8
0
0
0
8
8
% R
% Ser:
8
47
0
0
0
0
8
0
0
0
8
0
8
0
8
% S
% Thr:
0
0
8
0
0
24
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
8
0
8
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _