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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS3
All Species:
39.09
Human Site:
Y375
Identified Species:
71.67
UniProt:
Q9Y6X2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6X2
NP_006090.2
628
68017
Y375
V
C
D
K
K
A
P
Y
E
S
L
I
I
D
G
Chimpanzee
Pan troglodytes
XP_523109
766
83908
Y498
V
C
D
K
K
A
P
Y
E
H
L
I
I
D
G
Rhesus Macaque
Macaca mulatta
XP_001095153
700
75283
Y447
V
C
D
K
K
A
P
Y
E
S
L
I
I
D
G
Dog
Lupus familis
XP_540278
628
68106
Y375
V
C
D
K
K
A
P
Y
E
S
L
I
I
D
G
Cat
Felis silvestris
Mouse
Mus musculus
O54714
628
68299
Y375
V
C
D
K
K
A
P
Y
E
S
L
I
I
D
G
Rat
Rattus norvegicus
O70260
628
68345
Y375
V
C
D
K
K
A
P
Y
E
S
L
I
I
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516107
756
82793
Y482
V
C
D
K
K
A
P
Y
E
H
L
I
I
D
G
Chicken
Gallus gallus
NP_001026627
564
62782
T317
A
L
I
K
E
K
L
T
A
D
P
D
S
E
I
Frog
Xenopus laevis
NP_001086078
633
69985
Y382
V
C
D
K
K
A
P
Y
D
T
L
I
I
D
G
Zebra Danio
Brachydanio rerio
XP_688159
659
71801
Y383
V
C
D
K
K
A
P
Y
E
H
L
I
I
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
Y476
V
C
S
S
N
C
P
Y
D
R
L
I
V
D
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
V411
I
C
L
K
N
Y
S
V
E
H
V
I
V
D
P
Baker's Yeast
Sacchar. cerevisiae
Q12216
726
81160
F386
I
C
Q
H
P
I
K
F
D
Q
L
K
I
S
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.5
88.7
97.2
N.A.
96.9
96.6
N.A.
51.7
57.7
71.2
57.2
N.A.
N.A.
N.A.
22.9
N.A.
Protein Similarity:
100
60.9
89
97.7
N.A.
98
97.7
N.A.
61.9
68.7
81.1
68.2
N.A.
N.A.
N.A.
37.9
N.A.
P-Site Identity:
100
93.3
100
100
N.A.
100
100
N.A.
93.3
6.6
86.6
93.3
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
93.3
20
100
93.3
N.A.
N.A.
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
20.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.2
36.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
70
0
0
8
0
0
0
0
0
0
% A
% Cys:
0
93
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
70
0
0
0
0
0
24
8
0
8
0
85
8
% D
% Glu:
0
0
0
0
8
0
0
0
70
0
0
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% G
% His:
0
0
0
8
0
0
0
0
0
31
0
0
0
0
0
% H
% Ile:
16
0
8
0
0
8
0
0
0
0
0
85
77
0
8
% I
% Lys:
0
0
0
85
70
8
8
0
0
0
0
8
0
0
0
% K
% Leu:
0
8
8
0
0
0
8
0
0
0
85
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
77
0
0
0
8
0
0
0
8
% P
% Gln:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
0
0
8
8
0
0
8
0
0
39
0
0
8
8
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% T
% Val:
77
0
0
0
0
0
0
8
0
0
8
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _