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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS3
All Species:
17.88
Human Site:
Y562
Identified Species:
32.78
UniProt:
Q9Y6X2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6X2
NP_006090.2
628
68017
Y562
A
L
G
H
F
F
Q
Y
R
G
T
P
S
H
F
Chimpanzee
Pan troglodytes
XP_523109
766
83908
H691
S
D
D
Q
D
L
L
H
S
S
R
F
F
P
Y
Rhesus Macaque
Macaca mulatta
XP_001095153
700
75283
Y634
A
L
G
H
F
F
Q
Y
R
G
T
P
S
H
F
Dog
Lupus familis
XP_540278
628
68106
Y562
A
L
G
H
F
F
Q
Y
R
G
T
P
S
H
F
Cat
Felis silvestris
Mouse
Mus musculus
O54714
628
68299
Y562
T
L
G
H
F
F
Q
Y
R
G
T
P
S
H
F
Rat
Rattus norvegicus
O70260
628
68345
F562
T
L
G
H
F
F
Q
F
R
G
T
P
P
H
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516107
756
82793
L678
S
A
S
D
E
Q
D
L
L
H
S
S
R
F
F
Chicken
Gallus gallus
NP_001026627
564
62782
S502
L
N
L
P
H
Q
A
S
P
V
S
R
T
P
S
Frog
Xenopus laevis
NP_001086078
633
69985
Y571
S
L
S
H
F
F
Q
Y
R
G
P
P
A
H
Y
Zebra Danio
Brachydanio rerio
XP_688159
659
71801
D575
A
S
A
S
A
S
E
D
H
E
L
L
L
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
Q674
A
L
N
K
I
G
E
Q
S
A
N
S
S
T
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
H699
S
G
G
L
V
G
L
H
H
H
S
P
L
N
C
Baker's Yeast
Sacchar. cerevisiae
Q12216
726
81160
L625
L
L
G
I
E
G
D
L
P
P
I
P
P
V
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.5
88.7
97.2
N.A.
96.9
96.6
N.A.
51.7
57.7
71.2
57.2
N.A.
N.A.
N.A.
22.9
N.A.
Protein Similarity:
100
60.9
89
97.7
N.A.
98
97.7
N.A.
61.9
68.7
81.1
68.2
N.A.
N.A.
N.A.
37.9
N.A.
P-Site Identity:
100
0
100
100
N.A.
93.3
80
N.A.
6.6
0
66.6
6.6
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
20
100
100
N.A.
93.3
86.6
N.A.
20
13.3
86.6
20
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
20.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.2
36.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
8
8
0
8
0
8
0
0
8
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
8
8
8
8
0
16
8
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
16
0
16
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
47
47
0
8
0
0
0
8
8
8
47
% F
% Gly:
0
8
54
0
0
24
0
0
0
47
0
0
0
0
0
% G
% His:
0
0
0
47
8
0
0
16
16
16
0
0
0
47
0
% H
% Ile:
0
0
0
8
8
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
16
62
8
8
0
8
16
16
8
0
8
8
16
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
0
0
0
0
8
0
0
16
0
% N
% Pro:
0
0
0
8
0
0
0
0
16
8
8
62
16
16
0
% P
% Gln:
0
0
0
8
0
16
47
8
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
47
0
8
8
8
0
8
% R
% Ser:
31
8
16
8
0
8
0
8
16
8
24
16
39
0
8
% S
% Thr:
16
0
0
0
0
0
0
0
0
0
39
0
8
8
0
% T
% Val:
0
0
0
0
8
0
0
0
0
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
39
0
0
0
0
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _