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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM169A
All Species:
17.27
Human Site:
Y281
Identified Species:
47.5
UniProt:
Q9Y6X4
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y6X4
NP_056381.1
670
74955
Y281
K
R
P
M
S
G
E
Y
G
P
A
S
V
P
E
Chimpanzee
Pan troglodytes
XP_517703
840
92266
Y451
K
R
P
M
S
G
E
Y
G
P
A
S
V
P
E
Rhesus Macaque
Macaca mulatta
XP_001099174
815
89239
Y426
K
R
P
M
S
G
E
Y
G
P
A
Y
V
P
E
Dog
Lupus familis
XP_544374
670
74886
Y281
K
R
S
M
S
G
E
Y
G
L
A
S
V
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5XG69
665
73240
G279
E
A
T
R
P
V
S
G
E
Y
G
L
A
A
V
Rat
Rattus norvegicus
XP_002725959
665
73265
Y281
K
R
P
V
S
G
E
Y
G
P
A
A
V
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513553
667
74067
A281
N
E
E
C
V
T
A
A
T
P
A
Y
E
L
G
Chicken
Gallus gallus
XP_429149
687
76212
H298
V
S
F
Q
T
A
D
H
F
W
Q
S
A
A
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919339
826
91758
K326
R
S
S
E
H
K
H
K
K
R
P
R
E
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.6
80
90.4
N.A.
80
78.3
N.A.
71.4
53.1
N.A.
33.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
79.6
80.7
92.8
N.A.
88.2
87.6
N.A.
81.6
65
N.A.
51.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
0
86.6
N.A.
13.3
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
6.6
100
N.A.
13.3
26.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
12
12
12
0
0
67
12
23
23
0
% A
% Cys:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% D
% Glu:
12
12
12
12
0
0
56
0
12
0
0
0
23
12
56
% E
% Phe:
0
0
12
0
0
0
0
0
12
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
56
0
12
56
0
12
0
0
0
12
% G
% His:
0
0
0
0
12
0
12
12
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
56
0
0
0
0
12
0
12
12
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
12
0
12
0
12
0
% L
% Met:
0
0
0
45
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% N
% Pro:
0
0
45
0
12
0
0
0
0
56
12
0
0
56
12
% P
% Gln:
0
0
0
12
0
0
0
0
0
0
12
0
0
0
0
% Q
% Arg:
12
56
0
12
0
0
0
0
0
12
0
12
0
0
0
% R
% Ser:
0
23
23
0
56
0
12
0
0
0
0
45
0
0
0
% S
% Thr:
0
0
12
0
12
12
0
0
12
0
0
0
0
0
0
% T
% Val:
12
0
0
12
12
12
0
0
0
0
0
0
56
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
56
0
12
0
23
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _