PhosphoNET Kinase Predictor

Note - First set of Kinase Predictor V2 Scores are based on analysis of just the phosphosite independent of any other neighbouring phosphosites that might be recognized by the kinase shown. The maximum score possible is 1000. For the second set in the rightmost columns, the influence of the neighbouring phsophosites are also considered. These prediction scores are not scaled to a maximum of 1000.

Phosphosite
Human Protein:	TOP1
Human P-Site:	S112
P-Site Sequence:	EKENGFSSPPQIKDE
UniProt:	P11387
Intern. Prot. ID:	IPI00413611

Protein Kinase Match	Human Kinase Short Name	Human UniProt. ID	Kinase Predictor V2 Score	Human Kinase Short Name	Human UniProt. ID	Kinase Predictor V2 Score - Proximity
Kinase 1:	JNK2 (MAPK9)	P45984	460	ERK2 (MAPK1)	P28482	1560
Kinase 2:	CDK1 (CDC2)	P06493	460	CDK1 (CDC2)	P06493	1559
Kinase 3:	JNK1 (MAPK8)	P45983	460	ERK1	P27361	1537
Kinase 4:	JNK3 (MAPK10)	P53779	460	NEK4 (STK2)	P51957	1504
Kinase 5:	CDK2	P24941	459	ICK	Q9UPZ9	1498
Kinase 6:	ERK1	P27361	455	GSK3A	P49840	1492
Kinase 7:	ERK2 (MAPK1)	P28482	451	JNK1 (MAPK8)	P45983	1488
Kinase 8:	p38d MAPK (MAPK13)	O15264	451	JNK3 (MAPK10)	P53779	1488
Kinase 9:	CDK3	Q00526	436	ERK7 (BI916334)	Q8TD08	1487
Kinase 10:	p38b MAPK (MAPK11)	Q15759	435	JNK2 (MAPK9)	P45984	1483
Kinase 11:	p38g MAPK (MAPK12)	P53778	434	MAK	P20794	1467
Kinase 12:	ERK5 (MAPK7)	Q13164	430	CDK3	Q00526	1463
Kinase 13:	ERK7 (BI916334)	Q8TD08	429	NEK8 (AI086865)	Q86SG6	1447
Kinase 14:	p38a MAPK (MAPK14)	Q16539	428	CDK5	Q00535	1446
Kinase 15:	CDK5	Q00535	426	PFTAIRE2 (ALS2CR7)	Q96Q40	1440
Kinase 16:	CDKL5 (STK9)	O76039	421	CDK2	P24941	1435
Kinase 17:	PCTAIRE2 (PCTK2)	Q00537	419	GSK3B	P49841	1424
Kinase 18:	ICK	Q9UPZ9	418	CDK7	P50613	1423
Kinase 19:	MAK	P20794	417	p38g MAPK (MAPK12)	P53778	1420
Kinase 20:	CDKL1	Q00532	417	CHED (CDC2L5)	Q14004	1415
Kinase 21:	CDKL4 (AA626859)	Q5MAI5	415	PCTAIRE2 (PCTK2)	Q00537	1413
Kinase 22:	CDK10	Q15131	412	p38d MAPK (MAPK13)	O15264	1412
Kinase 23:	CHED (CDC2L5)	Q14004	411	PFTAIRE1 (PFTK1)	O94921	1406
Kinase 24:	PCTAIRE3	Q07002	407	CRK7 (CRKRS)	Q9NYV4	1398
Kinase 25:	PCTAIRE1 (PCTK1)	Q04735	407	CDKL5 (STK9)	O76039	1395
Kinase 26:	CDKL2	Q92772	405	PCTAIRE1 (PCTK1)	Q04735	1387
Kinase 27:	CDK7	P50613	402	NEK1	Q96PY6	1385
Kinase 28:	PFTAIRE2 (ALS2CR7)	Q96Q40	401	PCTAIRE3	Q07002	1382
Kinase 29:	CRK7 (CRKRS)	Q9NYV4	396	p38b MAPK (MAPK11)	Q15759	1381
Kinase 30:	GSK3A	P49840	389	CDK10	Q15131	1370
Kinase 31:	PFTAIRE1 (PFTK1)	O94921	385	ERK5 (MAPK7)	Q13164	1366
Kinase 32:	CDKL3	Q8IVW4	382	CDKL4 (AA626859)	Q5MAI5	1362
Kinase 33:	GSK3B	P49841	367	PITSLRE (CDC2L1)	Q9UQ88	1357
Kinase 34:	PITSLRE (CDC2L1)	Q9UQ88	360	CDKL1	Q00532	1355
Kinase 35:	NLK	Q9UBE8	358	CDKL2	Q92772	1342
Kinase 36:	MOK (RAGE)	Q9UQ07	356	MOK (RAGE)	Q9UQ07	1338
Kinase 37:	CDK4	P11802	349	p38a MAPK (MAPK14)	Q16539	1334
Kinase 38:	CDK6	Q00534	348	CDKL3	Q8IVW4	1333
Kinase 39:	DYRK2	Q92630	333	NIK (MAP3K14)	Q99558	1326
Kinase 40:	CDK9	P50750	328	CLK2	P49760	1320
Kinase 41:	VRK3	Q8IV63	321	DYRK2	Q92630	1318
Kinase 42:	HIPK1 (BE180036)	Q86Z02	311	GAK	O14976	1298
Kinase 43:	CCRK	Q8IZL9	309	CK2a1 (CSNK2A1)	P68400	1292
Kinase 44:	DYRK3	O43781	308	RAF1	P04049	1286
Kinase 45:	CDK11 (DPK)	Q9BWU1	306	CDC7 (CDC7L1)	O00311	1284
Kinase 46:	PIM1	P11309	305	SgK307	Q8IWB6	1277
Kinase 47:	CDK8	P49336	305	SPEG (KIAA1297)	Q15772	1275
Kinase 48:	CYGD (GUCY2D)	Q02846	302	CK2a2 (CSNK2A2)	P19784	1274
Kinase 49:	DYRK1A	Q13627	302	DYRK4	Q9NR20	1270
Kinase 50:	RAF1	P04049	300	NLK	Q9UBE8	1266