PhosphoNET Kinase Predictor

Note - First set of Kinase Predictor V2 Scores are based on analysis of just the phosphosite independent of any other neighbouring phosphosites that might be recognized by the kinase shown. The maximum score possible is 1000. For the second set in the rightmost columns, the influence of the neighbouring phsophosites are also considered. These prediction scores are not scaled to a maximum of 1000.

Phosphosite
Human Protein:	TOP1
Human P-Site:	S250
P-Site Sequence:	DGKVMKLSPKAEEVA
UniProt:	P11387
Intern. Prot. ID:	IPI00413611

Protein Kinase Match	Human Kinase Short Name	Human UniProt. ID	Kinase Predictor V2 Score	Human Kinase Short Name	Human UniProt. ID	Kinase Predictor V2 Score - Proximity
Kinase 1:	JNK1 (MAPK8)	P45983	476	JNK1 (MAPK8)	P45983	322
Kinase 2:	JNK3 (MAPK10)	P53779	476	JNK3 (MAPK10)	P53779	322
Kinase 3:	p38d MAPK (MAPK13)	O15264	465	p38d MAPK (MAPK13)	O15264	311
Kinase 4:	ERK2 (MAPK1)	P28482	453	ERK2 (MAPK1)	P28482	301
Kinase 5:	JNK2 (MAPK9)	P45984	443	JNK2 (MAPK9)	P45984	299
Kinase 6:	p38a MAPK (MAPK14)	Q16539	442	CDK2	P24941	297
Kinase 7:	CDK2	P24941	439	p38a MAPK (MAPK14)	Q16539	295
Kinase 8:	ERK1	P27361	438	ERK1	P27361	291
Kinase 9:	p38g MAPK (MAPK12)	P53778	435	ERK7 (BI916334)	Q8TD08	290
Kinase 10:	ERK5 (MAPK7)	Q13164	431	p38g MAPK (MAPK12)	P53778	290
Kinase 11:	ERK7 (BI916334)	Q8TD08	429	ERK5 (MAPK7)	Q13164	285
Kinase 12:	CDKL2	Q92772	420	CDK3	Q00526	278
Kinase 13:	CDK3	Q00526	409	CDKL2	Q92772	277
Kinase 14:	p38b MAPK (MAPK11)	Q15759	403	p38b MAPK (MAPK11)	Q15759	270
Kinase 15:	CDKL4 (AA626859)	Q5MAI5	402	CDKL4 (AA626859)	Q5MAI5	267
Kinase 16:	CDKL1	Q00532	401	CHED (CDC2L5)	Q14004	267
Kinase 17:	CHED (CDC2L5)	Q14004	398	CDK1 (CDC2)	P06493	267
Kinase 18:	CRK7 (CRKRS)	Q9NYV4	394	PFTAIRE2 (ALS2CR7)	Q96Q40	267
Kinase 19:	PCTAIRE2 (PCTK2)	Q00537	394	PCTAIRE2 (PCTK2)	Q00537	267
Kinase 20:	PCTAIRE1 (PCTK1)	Q04735	393	CDK5	Q00535	266
Kinase 21:	CDKL5 (STK9)	O76039	393	PCTAIRE1 (PCTK1)	Q04735	266
Kinase 22:	PCTAIRE3	Q07002	392	PCTAIRE3	Q07002	266
Kinase 23:	MAK	P20794	392	CRK7 (CRKRS)	Q9NYV4	266
Kinase 24:	CDK5	Q00535	392	CDKL1	Q00532	265
Kinase 25:	CDK1 (CDC2)	P06493	390	CDKL5 (STK9)	O76039	264
Kinase 26:	PFTAIRE2 (ALS2CR7)	Q96Q40	389	mTOR/FRAP	P42345	264
Kinase 27:	CDKL3	Q8IVW4	386	MAK	P20794	261
Kinase 28:	ICK	Q9UPZ9	386	ICK	Q9UPZ9	257
Kinase 29:	mTOR/FRAP	P42345	383	PFTAIRE1 (PFTK1)	O94921	256
Kinase 30:	PFTAIRE1 (PFTK1)	O94921	377	CDKL3	Q8IVW4	254
Kinase 31:	CDK7	P50613	371	CDK7	P50613	247
Kinase 32:	CDK4	P11802	368	CDK10	Q15131	247
Kinase 33:	CDK10	Q15131	366	CDK4	P11802	247
Kinase 34:	VRK3	Q8IV63	356	VRK3	Q8IV63	238
Kinase 35:	CDK6	Q00534	342	CDK8	P49336	235
Kinase 36:	CDK8	P49336	342	PITSLRE (CDC2L1)	Q9UQ88	231
Kinase 37:	DYRK2	Q92630	337	CDK11 (DPK)	Q9BWU1	231
Kinase 38:	PITSLRE (CDC2L1)	Q9UQ88	336	CK2a2 (CSNK2A2)	P19784	231
Kinase 39:	CDK11 (DPK)	Q9BWU1	334	CYGD (GUCY2D)	Q02846	229
Kinase 40:	MOK (RAGE)	Q9UQ07	333	CDK6	Q00534	228
Kinase 41:	CYGD (GUCY2D)	Q02846	331	DYRK2	Q92630	226
Kinase 42:	NLK	Q9UBE8	329	CK2a1 (CSNK2A1)	P68400	226
Kinase 43:	DYRK3	O43781	326	MOK (RAGE)	Q9UQ07	220
Kinase 44:	CK2a2 (CSNK2A2)	P19784	325	DYRK3	O43781	220
Kinase 45:	NIK (MAP3K14)	Q99558	320	NLK	Q9UBE8	219
Kinase 46:	CK2a1 (CSNK2A1)	P68400	317	NIK (MAP3K14)	Q99558	216
Kinase 47:	GSK3B	P49841	312	NEK4 (STK2)	P51957	210
Kinase 48:	GSK3A	P49840	312	LZK (MAP3K13)	O43283	210
Kinase 49:	NEK4 (STK2)	P51957	306	GSK3B	P49841	210
Kinase 50:	LZK (MAP3K13)	O43283	306	GSK3A	P49840	209