PhosphoNET Kinase Predictor

Note - First set of Kinase Predictor V2 Scores are based on analysis of just the phosphosite independent of any other neighbouring phosphosites that might be recognized by the kinase shown. The maximum score possible is 1000. For the second set in the rightmost columns, the influence of the neighbouring phsophosites are also considered. These prediction scores are not scaled to a maximum of 1000.

Phosphosite
Human Protein:	TOP1
Human P-Site:	S298
P-Site Sequence:	KNIITNLSKCDFTQM
UniProt:	P11387
Intern. Prot. ID:	IPI00413611

Protein Kinase Match	Human Kinase Short Name	Human UniProt. ID	Kinase Predictor V2 Score	Human Kinase Short Name	Human UniProt. ID	Kinase Predictor V2 Score - Proximity
Kinase 1:	p38d MAPK (MAPK13)	O15264	316	ATR	Q13535	257
Kinase 2:	SgK307	Q8IWB6	313	p38d MAPK (MAPK13)	O15264	254
Kinase 3:	PDK1 (PDPK1)	O15530	310	DNAPK/PRKDC	P78527	234
Kinase 4:	MSK1 (RPS6KA5)	O75582	304	PDK1 (PDPK1)	O15530	234
Kinase 5:	CAMK4	Q16566	304	CAMK4	Q16566	230
Kinase 6:	p38g MAPK (MAPK12)	P53778	290	SgK307	Q8IWB6	227
Kinase 7:	VRK3	Q8IV63	289	VRK3	Q8IV63	222
Kinase 8:	ANPb (NPR2)	P20594	288	p38g MAPK (MAPK12)	P53778	222
Kinase 9:	SPEG (KIAA1297)	Q15772	286	JNK1 (MAPK8)	P45983	222
Kinase 10:	ANPa (NPR1)	P16066	285	JNK3 (MAPK10)	P53779	222
Kinase 11:	RSK2 (RPS6KA3)	P51812	285	p38a MAPK (MAPK14)	Q16539	222
Kinase 12:	p38a MAPK (MAPK14)	Q16539	283	ANPb (NPR2)	P20594	221
Kinase 13:	NEK10	Q6ZWH5	282	MSK1 (RPS6KA5)	O75582	221
Kinase 14:	RSK2 (RPS6KA3)	P51812	282	NEK10	Q6ZWH5	216
Kinase 15:	RSK3 (RPS6KA1)	Q15349	282	SPEG (KIAA1297)	Q15772	215
Kinase 16:	RSK1 (RPS6KA2)	Q15418	282	ANPa (NPR1)	P16066	213
Kinase 17:	Plk4 (STK18)	Q64702	282	RSK2 (RPS6KA3)	P51812	213
Kinase 18:	NEK5	Q6P3R8	281	Plk4 (STK18)	Q64702	213
Kinase 19:	CDKL1	Q00532	280	VRK1	Q99986	213
Kinase 20:	CDKL4 (AA626859)	Q5MAI5	278	NEK5	Q6P3R8	212
Kinase 21:	JNK1 (MAPK8)	P45983	278	TGFBR2	P37173	209
Kinase 22:	JNK3 (MAPK10)	P53779	278	GPRK4 (GPRK2L)	P32298	208
Kinase 23:	SGK2	Q9HBY8	278	CDKL4 (AA626859)	Q5MAI5	208
Kinase 24:	RSK4 (RPS6KA6)	Q9UK32	277	NEK8 (AI086865)	Q86SG6	208
Kinase 25:	BRSK2 (AL538014)	Q8IWQ3	276	MSK2 (RPS6KA4)	O75676	207
Kinase 26:	BRSK1 (KIAA1811)	Q8TDC3	276	PFTAIRE1 (PFTK1)	O94921	207
Kinase 27:	CDKL3	Q8IVW4	276	RSK3 (RPS6KA1)	Q15349	207
Kinase 28:	MAPKAPK2	P49137	275	RSK2 (RPS6KA3)	P51812	207
Kinase 29:	MSK2 (RPS6KA4)	O75676	275	JNK2 (MAPK9)	P45984	206
Kinase 30:	PSKH1 (HUMPSKB)	P11801	274	RSK1 (RPS6KA2)	Q15418	206
Kinase 31:	CDKL2	Q92772	274	CDKL1	Q00532	206
Kinase 32:	ERK2 (MAPK1)	P28482	274	CDK2	P24941	206
Kinase 33:	PKCi (PRKCI)	P41743	273	BRSK2 (AL538014)	Q8IWQ3	206
Kinase 34:	SGK	O00141	273	BRSK1 (KIAA1811)	Q8TDC3	206
Kinase 35:	RSK1 (RPS6KA2)	Q15418	271	SGK2	Q9HBY8	205
Kinase 36:	CHK2 (CHEK2)	O96017	271	GCK (MAP4K2)	Q12851	204
Kinase 37:	DCAMKL1	O15075	271	DCAMKL1	O15075	204
Kinase 38:	VRK1	Q99986	270	RSK1 (RPS6KA2)	Q15418	204
Kinase 39:	RSK3 (RPS6KA1)	Q15349	270	CAMK2b	Q13554	204
Kinase 40:	DCAMKL3 (KIAA1765)	Q9C098	270	KHS2 (MAP4K3)	Q8IVH8	204
Kinase 41:	CaMK1a (CAMK1)	Q14012	269	IKKb (IKBKINASE)	O14920	204
Kinase 42:	GPRK4 (GPRK2L)	P32298	269	MRCKb (CDC42BPB)	Q9Y5S2	204
Kinase 43:	RSK4 (RPS6KA6)	Q9UK32	269	CASK	O14936	203
Kinase 44:	CAMK1b	Q6P2M8	268	RSK4 (RPS6KA6)	Q9UK32	203
Kinase 45:	CaMK1d (LOC57118)	Q8IU85	268	MRCKa (PK428)	Q5VT25	203
Kinase 46:	SPEG (KIAA1297)	Q15772	268	MAPKAPK2	P49137	203
Kinase 47:	DCAMKL2 (BI035543)	Q8N568	268	SPEG (KIAA1297)	Q15772	203
Kinase 48:	IKKE	Q14164	267	GPRK7	Q8WTQ7	203
Kinase 49:	MAPKAPK3	Q16644	267	CDKL3	Q8IVW4	203
Kinase 50:	PFTAIRE1 (PFTK1)	O94921	266	CDKL2	Q92772	202