PhosphoNET Kinase Predictor

Note - First set of Kinase Predictor V2 Scores are based on analysis of just the phosphosite independent of any other neighbouring phosphosites that might be recognized by the kinase shown. The maximum score possible is 1000. For the second set in the rightmost columns, the influence of the neighbouring phsophosites are also considered. These prediction scores are not scaled to a maximum of 1000.

Phosphosite
Human Protein:	ISL1
Human P-Site:	S326
P-Site Sequence:	PGSNSTGSEVASMSS
UniProt:	P61371
Intern. Prot. ID:	IPI00025071

Protein Kinase Match	Human Kinase Short Name	Human UniProt. ID	Kinase Predictor V2 Score	Human Kinase Short Name	Human UniProt. ID	Kinase Predictor V2 Score - Proximity
Kinase 1:	RSK2 (RPS6KA3)	P51812	349	mTOR/FRAP	P42345	2448
Kinase 2:	RHOK (Grk1)	Q15835	344	p38a MAPK (MAPK14)	Q16539	2387
Kinase 3:	CDK10	Q15131	341	ERK1	P27361	2260
Kinase 4:	RSK1 (RPS6KA2)	Q15418	338	JNK1 (MAPK8)	P45983	2224
Kinase 5:	RSK4 (RPS6KA6)	Q9UK32	336	JNK3 (MAPK10)	P53779	2224
Kinase 6:	RSK3 (RPS6KA1)	Q15349	335	CDK1 (CDC2)	P06493	2206
Kinase 7:	mTOR/FRAP	P42345	335	p38b MAPK (MAPK11)	Q15759	2198
Kinase 8:	RSK2 (RPS6KA3)	P51812	333	p38d MAPK (MAPK13)	O15264	2190
Kinase 9:	p38a MAPK (MAPK14)	Q16539	333	JNK2 (MAPK9)	P45984	2159
Kinase 10:	MAST4 (KIAA0303)	O15021	330	ERK2 (MAPK1)	P28482	2156
Kinase 11:	GSK3B	P49841	329	CDK7	P50613	2153
Kinase 12:	IKKE	Q14164	329	CDKL5 (STK9)	O76039	2124
Kinase 13:	CDK7	P50613	329	CK1a1 (CSNK1A1)	P48729	2100
Kinase 14:	PFTAIRE2 (ALS2CR7)	Q96Q40	325	PFTAIRE1 (PFTK1)	O94921	2091
Kinase 15:	DAPK2	Q9UIK4	325	PCTAIRE3	Q07002	2090
Kinase 16:	ERK1	P27361	324	CDK10	Q15131	2090
Kinase 17:	CDK9	P50750	322	ERK7 (BI916334)	Q8TD08	2083
Kinase 18:	GSK3A	P49840	321	p38g MAPK (MAPK12)	P53778	2077
Kinase 19:	ERK2 (MAPK1)	P28482	320	CK1d1 (CSNK1D)	P48730	2058
Kinase 20:	p70S6K (RPS6KB1)	P23443	318	CK1e1 (CSNK1E)	P49674	2058
Kinase 21:	PITSLRE (CDC2L1)	Q9UQ88	314	ERK5 (MAPK7)	Q13164	2054
Kinase 22:	ERK5 (MAPK7)	Q13164	314	PCTAIRE2 (PCTK2)	Q00537	2050
Kinase 23:	PSKH1 (HUMPSKB)	P11801	311	PCTAIRE1 (PCTK1)	Q04735	2041
Kinase 24:	MAST3 (KIAA0561)	O60307	311	ATR	Q13535	2041
Kinase 25:	Plk4 (STK18)	Q64702	311	CDKL4 (AA626859)	Q5MAI5	2029
Kinase 26:	AKT3	Q9Y243	311	CDK3	Q00526	2026
Kinase 27:	CDKL5 (STK9)	O76039	306	PFTAIRE2 (ALS2CR7)	Q96Q40	2026
Kinase 28:	PCTAIRE3	Q07002	306	NuaK1 (KIAA0537)	O60285	2012
Kinase 29:	MAST1 (KIAA0973)	Q9Y2H9	305	IKKE	Q14164	2012
Kinase 30:	PCTAIRE1 (PCTK1)	Q04735	304	ICK	Q9UPZ9	2012
Kinase 31:	MSK2 (RPS6KA4)	O75676	304	RSK1 (RPS6KA2)	Q15418	2007
Kinase 32:	p38b MAPK (MAPK11)	Q15759	304	PITSLRE (CDC2L1)	Q9UQ88	2006
Kinase 33:	Nuak2 (DKFZP434J037)	Q9H093	303	CDK2	P24941	1999
Kinase 34:	NuaK1 (KIAA0537)	O60285	303	NLK	Q9UBE8	1996
Kinase 35:	AKT1	P31749	302	RSK2 (RPS6KA3)	P51812	1984
Kinase 36:	MAK	P20794	302	MAK	P20794	1983
Kinase 37:	AKT2	P31751	302	RSK4 (RPS6KA6)	Q9UK32	1981
Kinase 38:	ROCK1	Q13464	301	Plk4 (STK18)	Q64702	1980
Kinase 39:	HSER (GUCY2C)	P25092	301	RSK3 (RPS6KA1)	Q15349	1973
Kinase 40:	PKG2 (PRKG2)	Q13237	299	MAST4 (KIAA0303)	O15021	1969
Kinase 41:	p70S6Kb (RPS6KB2)	Q9UBS0	299	CDKL3	Q8IVW4	1966
Kinase 42:	NIK (MAP3K14)	Q99558	298	TBK1	Q9UHD2	1964
Kinase 43:	SGK3 (SGKL)	Q96BR1	297	ANPa (NPR1)	P16066	1933
Kinase 44:	TBK1	Q9UHD2	297	CDKL1	Q00532	1932
Kinase 45:	PCTAIRE2 (PCTK2)	Q00537	297	MAST1 (KIAA0973)	Q9Y2H9	1918
Kinase 46:	CK1a1 (CSNK1A1)	P48729	295	CDK5	Q00535	1914
Kinase 47:	ULK1	O75385	295	p70S6K (RPS6KB1)	P23443	1911
Kinase 48:	PINK1	Q9BXM7	294	RSK2 (RPS6KA3)	P51812	1908
Kinase 49:	MAST2 (KIAA0807)	Q6P0Q8	294	SgK307	Q8IWB6	1906
Kinase 50:	ICK	Q9UPZ9	293	GSK3A	P49840	1894