PhosphoNET Kinase Predictor

Note - First set of Kinase Predictor V2 Scores are based on analysis of just the phosphosite independent of any other neighbouring phosphosites that might be recognized by the kinase shown. The maximum score possible is 1000. For the second set in the rightmost columns, the influence of the neighbouring phsophosites are also considered. These prediction scores are not scaled to a maximum of 1000.

Phosphosite
Human Protein:	TOP1
Human P-Site:	S686
P-Site Sequence:	KTKKVVESKKKAVQR
UniProt:	P11387
Intern. Prot. ID:	IPI00413611

Protein Kinase Match	Human Kinase Short Name	Human UniProt. ID	Kinase Predictor V2 Score	Human Kinase Short Name	Human UniProt. ID	Kinase Predictor V2 Score - Proximity
Kinase 1:	CLK2	P49760	251	CLK2	P49760	161
Kinase 2:	CLK4	Q9HAZ1	250	CLK4	Q9HAZ1	160
Kinase 3:	PKCz (PRKCZ)	Q05513	248	PKCz (PRKCZ)	Q05513	159
Kinase 4:	CLK1	P49759	247	CLK1	P49759	159
Kinase 5:	CDKL2	Q92772	239	CDKL2	Q92772	154
Kinase 6:	MSK1 (RPS6KA5)	O75582	236	MSK1 (RPS6KA5)	O75582	151
Kinase 7:	CDKL3	Q8IVW4	236	CDKL3	Q8IVW4	151
Kinase 8:	DMPK2 (HSMDPKIN)	Q6DT37	234	DMPK2 (HSMDPKIN)	Q6DT37	150
Kinase 9:	ATR	Q13535	232	ATR	Q13535	149
Kinase 10:	NDR2 (KIAA0965)	Q9Y2H1	231	NDR2 (KIAA0965)	Q9Y2H1	148
Kinase 11:	SgK307	Q8IWB6	231	SgK307	Q8IWB6	148
Kinase 12:	PKCi (PRKCI)	P41743	230	PKCi (PRKCI)	P41743	148
Kinase 13:	PKCt (PRKCQ)	Q04759	230	PKCt (PRKCQ)	Q04759	147
Kinase 14:	NDR1 (NDR)	Q15208	229	NDR1 (NDR)	Q15208	147
Kinase 15:	RHOK (Grk1)	Q15835	227	RHOK (Grk1)	Q15835	146
Kinase 16:	PKN3 (PKNBETA)	Q6P5Z2	227	PKN3 (PKNBETA)	Q6P5Z2	145
Kinase 17:	MEK5 (MAP2K5)	Q13163	226	MEK5 (MAP2K5)	Q13163	145
Kinase 18:	PKCg (PRKCG)	P05129	223	PKCg (PRKCG)	P05129	143
Kinase 19:	AurA (STK15)	O14965	223	AurA (STK15)	O14965	143
Kinase 20:	STK33	Q9BYT3	223	STK33	Q9BYT3	143
Kinase 21:	AurC (STK13)	Q9UQB9	222	AurC (STK13)	Q9UQB9	142
Kinase 22:	CRIK (BF380737)	O14578	222	CRIK (BF380737)	O14578	142
Kinase 23:	GPRK4 (GPRK2L)	P32298	221	GPRK4 (GPRK2L)	P32298	142
Kinase 24:	BARK1 (ADRBK1, GRK2)	P25098	221	BARK1 (ADRBK1, GRK2)	P25098	142
Kinase 25:	MYO3B (BAB71011)	Q8WXR4	220	MYO3B (BAB71011)	Q8WXR4	141
Kinase 26:	DAPK3	O43293	220	DAPK3	O43293	141
Kinase 27:	SPEG (KIAA1297)	Q15772	220	SPEG (KIAA1297)	Q15772	141
Kinase 28:	CHED (CDC2L5)	Q14004	220	CHED (CDC2L5)	Q14004	141
Kinase 29:	DCAMKL1	O15075	218	DCAMKL1	O15075	140
Kinase 30:	GPRK7	Q8WTQ7	218	GPRK7	Q8WTQ7	140
Kinase 31:	COT (MAP3K8)	P41279	218	COT (MAP3K8)	P41279	140
Kinase 32:	CDK4	P11802	217	CDK4	P11802	139
Kinase 33:	SGK2	Q9HBY8	217	SGK2	Q9HBY8	139
Kinase 34:	smMLCK (MYLK)	Q15746	217	smMLCK (MYLK)	Q15746	139
Kinase 35:	caMLCK (MLCK)	Q32MK0	216	caMLCK (MLCK)	Q32MK0	139
Kinase 36:	PKCb (PRKCB1)	P05771	216	PKCb (PRKCB1)	P05771	139
Kinase 37:	CDKL4 (AA626859)	Q5MAI5	215	CDKL4 (AA626859)	Q5MAI5	138
Kinase 38:	PINK1	Q9BXM7	215	PINK1	Q9BXM7	138
Kinase 39:	PKCd (PRKCD)	Q05655	214	PKCd (PRKCD)	Q05655	137
Kinase 40:	MRCKa (PK428)	Q5VT25	214	MRCKa (PK428)	Q5VT25	137
Kinase 41:	MRCKb (CDC42BPB)	Q9Y5S2	214	MRCKb (CDC42BPB)	Q9Y5S2	137
Kinase 42:	CASK	O14936	214	CASK	O14936	137
Kinase 43:	PKCa (PRKCA)	P17252	214	PKCa (PRKCA)	P17252	137
Kinase 44:	CHK2 (CHEK2)	O96017	213	CHK2 (CHEK2)	O96017	137
Kinase 45:	ROCK2	O75116	213	ROCK2	O75116	137
Kinase 46:	MYO3A	Q8NEV4	213	MYO3A	Q8NEV4	137
Kinase 47:	CK1a1 (CSNK1A1)	P48729	213	CK1a1 (CSNK1A1)	P48729	137
Kinase 48:	PKN1 (PRKCL1)	Q16512	213	PKN1 (PRKCL1)	Q16512	137
Kinase 49:	PKN2 (PRKCL2)	Q16513	213	PKN2 (PRKCL2)	Q16513	137
Kinase 50:	ROCK1	Q13464	212	ROCK1	Q13464	136