PhosphoNET Kinase Predictor

Note - First set of Kinase Predictor V2 Scores are based on analysis of just the phosphosite independent of any other neighbouring phosphosites that might be recognized by the kinase shown. The maximum score possible is 1000. For the second set in the rightmost columns, the influence of the neighbouring phsophosites are also considered. These prediction scores are not scaled to a maximum of 1000.

Phosphosite
Human Protein:	TOP1
Human P-Site:	Y538
P-Site Sequence:	GKDSIRYYNKVPVEK
UniProt:	P11387
Intern. Prot. ID:	IPI00413611

Protein Kinase Match	Human Kinase Short Name	Human UniProt. ID	Kinase Predictor V2 Score	Human Kinase Short Name	Human UniProt. ID	Kinase Predictor V2 Score - Proximity
Kinase 1:	MER (MERTK)	Q12866	424	MER (MERTK)	Q12866	272
Kinase 2:	JAK2	O60674	412	JAK2	O60674	265
Kinase 3:	BTK	Q06187	408	BTK	Q06187	262
Kinase 4:	ABL	P00519	406	ABL	P00519	261
Kinase 5:	ARG (ABL2)	P42684	403	ARG (ABL2)	P42684	259
Kinase 6:	MET (HGF Receptor)	P08581	400	MET (HGF Receptor)	P08581	257
Kinase 7:	KDR	P35968	387	KDR	P35968	248
Kinase 8:	Flt4 (VEGFR3)	P35918	386	Flt4 (VEGFR3)	P35918	248
Kinase 9:	FLT1	P17948	385	FLT1	P17948	247
Kinase 10:	ERBB4	Q15303	381	ERBB4	Q15303	244
Kinase 11:	TYRO3	Q06418	379	TYRO3	Q06418	243
Kinase 12:	EGFR	P00533	378	EGFR	P00533	242
Kinase 13:	ERBB2	P04626	377	ERBB2	P04626	242
Kinase 14:	FES	P07332	375	FES	P07332	241
Kinase 15:	JAK1_d2	P52332	374	JAK1_d2	P52332	240
Kinase 16:	KIT	P10721	372	KIT	P10721	239
Kinase 17:	RON	Q04912	370	RON	Q04912	238
Kinase 18:	SRM (SRMS)	Q9H3Y6	370	SRM (SRMS)	Q9H3Y6	237
Kinase 19:	IGF1R	P08069	370	IGF1R	P08069	237
Kinase 20:	FER	P16591	369	FER	P16591	237
Kinase 21:	AXL	P30530	369	AXL	P30530	237
Kinase 22:	RYK	P34925	368	RYK	P34925	236
Kinase 23:	INSR	P06213	368	INSR	P06213	236
Kinase 24:	ITK	Q08881	365	ITK	Q08881	234
Kinase 25:	BMX	P51813	364	BMX	P51813	234
Kinase 26:	FGFR4	P22455	364	FGFR4	P22455	233
Kinase 27:	IRR (INSRR)	P14616	363	IRR (INSRR)	P14616	233
Kinase 28:	TRKB (NTRK2)	Q16620	362	TRKB (NTRK2)	Q16620	232
Kinase 29:	TRKC (NTRK3)	Q16288	360	TRKC (NTRK3)	Q16288	231
Kinase 30:	ZAP70	P43403	360	ZAP70	P43403	231
Kinase 31:	FAK	Q05397	360	FAK	Q05397	231
Kinase 32:	TRKA (NTRK1)	P04629	359	TRKA (NTRK1)	P04629	231
Kinase 33:	ROS1	P08922	359	ROS1	P08922	230
Kinase 34:	PYK2 (PTK2B)	Q14289	358	PYK2 (PTK2B)	Q14289	230
Kinase 35:	FGFR1	P11362	357	FGFR1	P11362	229
Kinase 36:	FLT3	P36888	356	FLT3	P36888	228
Kinase 37:	FMS (CSF1R)	P07333	356	FMS (CSF1R)	P07333	228
Kinase 38:	FGFR2	P21802	356	FGFR2	P21802	228
Kinase 39:	FGFR3	P22607	356	FGFR3	P22607	228
Kinase 40:	EPHB4	P54760	355	EPHB4	P54760	228
Kinase 41:	TXK	P42681	355	TXK	P42681	228
Kinase 42:	RET	P07949	354	RET	P07949	227
Kinase 43:	ERBB3	P21860	354	ERBB3	P21860	227
Kinase 44:	JAK2	O60674	354	JAK2	O60674	227
Kinase 45:	TIE2 (TEK)	Q02763	353	TIE2 (TEK)	Q02763	226
Kinase 46:	TEC	P42680	351	TEC	P42680	225
Kinase 47:	BRK	Q13882	350	BRK	Q13882	224
Kinase 48:	PDGFRB	P09619	349	PDGFRB	P09619	224
Kinase 49:	EPHA2	P29317	349	EPHA2	P29317	224
Kinase 50:	CSK	P41240	349	CSK	P41240	224