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Updated November 2019
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Protein Info
Short Name:
C2orf67
Full Name:
Uncharacterized protein C2orf67
Alias:
Type:
Mass (Da):
112253
Number AA:
987
UniProt ID:
A0AUZ9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
T
P
A
L
R
E
A
T
A
K
G
I
S
F
S
Site 2
S14
E
A
T
A
K
G
I
S
F
S
S
L
P
S
T
Site 3
S16
T
A
K
G
I
S
F
S
S
L
P
S
T
M
E
Site 4
S17
A
K
G
I
S
F
S
S
L
P
S
T
M
E
S
Site 5
S20
I
S
F
S
S
L
P
S
T
M
E
S
D
K
M
Site 6
T21
S
F
S
S
L
P
S
T
M
E
S
D
K
M
L
Site 7
S24
S
L
P
S
T
M
E
S
D
K
M
L
Y
M
E
Site 8
Y29
M
E
S
D
K
M
L
Y
M
E
S
P
R
T
V
Site 9
S32
D
K
M
L
Y
M
E
S
P
R
T
V
D
E
K
Site 10
T35
L
Y
M
E
S
P
R
T
V
D
E
K
L
K
G
Site 11
T44
D
E
K
L
K
G
D
T
F
S
Q
M
L
G
F
Site 12
S46
K
L
K
G
D
T
F
S
Q
M
L
G
F
P
T
Site 13
T53
S
Q
M
L
G
F
P
T
P
E
P
T
L
N
T
Site 14
S70
V
N
L
K
H
F
G
S
P
Q
S
S
K
H
Y
Site 15
S73
K
H
F
G
S
P
Q
S
S
K
H
Y
Q
T
V
Site 16
S74
H
F
G
S
P
Q
S
S
K
H
Y
Q
T
V
F
Site 17
Y77
S
P
Q
S
S
K
H
Y
Q
T
V
F
L
M
R
Site 18
T79
Q
S
S
K
H
Y
Q
T
V
F
L
M
R
S
N
Site 19
S87
V
F
L
M
R
S
N
S
T
L
N
K
H
N
E
Site 20
S105
Q
K
K
L
G
E
P
S
C
N
K
L
K
N
I
Site 21
Y114
N
K
L
K
N
I
L
Y
N
G
S
N
I
Q
L
Site 22
S122
N
G
S
N
I
Q
L
S
K
I
C
L
S
H
S
Site 23
S127
Q
L
S
K
I
C
L
S
H
S
E
E
F
I
K
Site 24
S129
S
K
I
C
L
S
H
S
E
E
F
I
K
K
E
Site 25
S139
F
I
K
K
E
P
L
S
D
T
T
S
Q
C
M
Site 26
S143
E
P
L
S
D
T
T
S
Q
C
M
K
D
V
Q
Site 27
S205
K
K
I
V
P
G
H
S
N
V
P
V
S
S
S
Site 28
S210
G
H
S
N
V
P
V
S
S
S
A
A
E
K
E
Site 29
S212
S
N
V
P
V
S
S
S
A
A
E
K
E
E
E
Site 30
S236
S
K
Q
K
I
L
L
S
Q
A
R
R
T
Q
K
Site 31
T241
L
L
S
Q
A
R
R
T
Q
K
H
L
Q
M
L
Site 32
T274
H
Q
L
P
K
M
K
T
F
H
E
P
T
T
I
Site 33
T280
K
T
F
H
E
P
T
T
I
L
G
N
S
L
P
Site 34
T300
K
P
E
V
N
T
L
T
A
E
N
K
L
W
D
Site 35
T317
K
N
G
F
A
R
C
T
A
A
E
I
Q
R
F
Site 36
S341
H
V
E
E
G
L
D
S
D
A
T
D
S
S
S
Site 37
T344
E
G
L
D
S
D
A
T
D
S
S
S
D
D
D
Site 38
S346
L
D
S
D
A
T
D
S
S
S
D
D
D
L
D
Site 39
S347
D
S
D
A
T
D
S
S
S
D
D
D
L
D
E
Site 40
S348
S
D
A
T
D
S
S
S
D
D
D
L
D
E
Y
Site 41
Y355
S
D
D
D
L
D
E
Y
T
L
R
K
N
V
A
Site 42
T356
D
D
D
L
D
E
Y
T
L
R
K
N
V
A
V
Site 43
S380
V
D
R
A
R
V
G
S
R
W
T
W
L
Q
A
Site 44
T383
A
R
V
G
S
R
W
T
W
L
Q
A
Q
I
S
Site 45
S437
Q
F
A
D
Q
A
A
S
L
N
I
L
G
N
P
Site 46
S462
P
E
Q
D
F
E
M
S
P
S
S
P
T
L
L
Site 47
S464
Q
D
F
E
M
S
P
S
S
P
T
L
L
L
R
Site 48
S465
D
F
E
M
S
P
S
S
P
T
L
L
L
R
N
Site 49
T481
E
K
Q
S
A
Q
L
T
E
I
I
N
S
L
I
Site 50
T496
A
P
L
N
L
S
P
T
S
S
P
L
S
S
K
Site 51
S497
P
L
N
L
S
P
T
S
S
P
L
S
S
K
S
Site 52
S498
L
N
L
S
P
T
S
S
P
L
S
S
K
S
C
Site 53
S501
S
P
T
S
S
P
L
S
S
K
S
C
S
H
K
Site 54
S502
P
T
S
S
P
L
S
S
K
S
C
S
H
K
C
Site 55
S504
S
S
P
L
S
S
K
S
C
S
H
K
C
L
A
Site 56
S506
P
L
S
S
K
S
C
S
H
K
C
L
A
N
G
Site 57
Y515
K
C
L
A
N
G
I
Y
R
S
A
S
E
N
L
Site 58
S517
L
A
N
G
I
Y
R
S
A
S
E
N
L
D
E
Site 59
S519
N
G
I
Y
R
S
A
S
E
N
L
D
E
L
S
Site 60
S526
S
E
N
L
D
E
L
S
S
S
S
S
W
L
L
Site 61
S527
E
N
L
D
E
L
S
S
S
S
S
W
L
L
N
Site 62
S528
N
L
D
E
L
S
S
S
S
S
W
L
L
N
Q
Site 63
S530
D
E
L
S
S
S
S
S
W
L
L
N
Q
K
H
Site 64
T546
K
K
K
R
K
D
R
T
R
L
K
S
S
S
L
Site 65
S550
K
D
R
T
R
L
K
S
S
S
L
T
F
M
S
Site 66
S552
R
T
R
L
K
S
S
S
L
T
F
M
S
T
S
Site 67
T554
R
L
K
S
S
S
L
T
F
M
S
T
S
A
R
Site 68
S557
S
S
S
L
T
F
M
S
T
S
A
R
T
R
P
Site 69
T558
S
S
L
T
F
M
S
T
S
A
R
T
R
P
L
Site 70
S559
S
L
T
F
M
S
T
S
A
R
T
R
P
L
Q
Site 71
S567
A
R
T
R
P
L
Q
S
F
H
K
R
K
L
Y
Site 72
Y574
S
F
H
K
R
K
L
Y
R
L
S
P
T
F
Y
Site 73
S577
K
R
K
L
Y
R
L
S
P
T
F
Y
W
T
P
Site 74
T579
K
L
Y
R
L
S
P
T
F
Y
W
T
P
Q
T
Site 75
Y581
Y
R
L
S
P
T
F
Y
W
T
P
Q
T
L
P
Site 76
T583
L
S
P
T
F
Y
W
T
P
Q
T
L
P
S
K
Site 77
T586
T
F
Y
W
T
P
Q
T
L
P
S
K
E
T
A
Site 78
T598
E
T
A
F
L
N
T
T
Q
M
P
C
L
Q
S
Site 79
T608
P
C
L
Q
S
A
S
T
W
S
S
Y
E
H
N
Site 80
S611
Q
S
A
S
T
W
S
S
Y
E
H
N
S
E
S
Site 81
Y612
S
A
S
T
W
S
S
Y
E
H
N
S
E
S
Y
Site 82
S616
W
S
S
Y
E
H
N
S
E
S
Y
L
L
R
E
Site 83
S618
S
Y
E
H
N
S
E
S
Y
L
L
R
E
H
V
Site 84
S626
Y
L
L
R
E
H
V
S
E
L
D
S
S
F
H
Site 85
S630
E
H
V
S
E
L
D
S
S
F
H
S
V
L
S
Site 86
S634
E
L
D
S
S
F
H
S
V
L
S
L
P
S
D
Site 87
T650
P
L
H
F
H
F
E
T
L
L
K
K
T
E
I
Site 88
Y670
E
N
K
F
V
D
E
Y
I
I
S
P
S
P
V
Site 89
S673
F
V
D
E
Y
I
I
S
P
S
P
V
H
S
T
Site 90
S675
D
E
Y
I
I
S
P
S
P
V
H
S
T
L
N
Site 91
S679
I
S
P
S
P
V
H
S
T
L
N
Q
W
R
N
Site 92
Y688
L
N
Q
W
R
N
G
Y
S
P
I
C
K
P
Q
Site 93
S698
I
C
K
P
Q
I
R
S
E
S
S
A
Q
L
L
Site 94
S700
K
P
Q
I
R
S
E
S
S
A
Q
L
L
Q
G
Site 95
S714
G
R
K
K
R
H
L
S
E
T
A
L
G
E
R
Site 96
T716
K
K
R
H
L
S
E
T
A
L
G
E
R
T
K
Site 97
S727
E
R
T
K
L
E
E
S
D
F
Q
H
T
E
S
Site 98
T732
E
E
S
D
F
Q
H
T
E
S
G
S
H
S
N
Site 99
S734
S
D
F
Q
H
T
E
S
G
S
H
S
N
F
T
Site 100
S736
F
Q
H
T
E
S
G
S
H
S
N
F
T
A
V
Site 101
S738
H
T
E
S
G
S
H
S
N
F
T
A
V
S
N
Site 102
T741
S
G
S
H
S
N
F
T
A
V
S
N
V
N
V
Site 103
S744
H
S
N
F
T
A
V
S
N
V
N
V
L
S
R
Site 104
S750
V
S
N
V
N
V
L
S
R
I
Q
N
S
S
R
Site 105
S755
V
L
S
R
I
Q
N
S
S
R
N
T
A
R
R
Site 106
S756
L
S
R
I
Q
N
S
S
R
N
T
A
R
R
R
Site 107
T759
I
Q
N
S
S
R
N
T
A
R
R
R
L
R
S
Site 108
S766
T
A
R
R
R
L
R
S
E
S
S
Y
D
I
D
Site 109
S768
R
R
R
L
R
S
E
S
S
Y
D
I
D
N
I
Site 110
S769
R
R
L
R
S
E
S
S
Y
D
I
D
N
I
V
Site 111
Y770
R
L
R
S
E
S
S
Y
D
I
D
N
I
V
I
Site 112
Y792
A
K
L
E
K
L
Q
Y
K
E
I
L
T
P
S
Site 113
Y811
V
L
Q
P
L
D
E
Y
N
L
G
K
E
E
I
Site 114
S822
K
E
E
I
E
D
L
S
D
E
V
F
S
L
R
Site 115
S827
D
L
S
D
E
V
F
S
L
R
H
K
K
Y
E
Site 116
Y833
F
S
L
R
H
K
K
Y
E
E
R
E
Q
A
R
Site 117
S854
S
K
W
H
R
R
N
S
R
A
Y
S
K
N
V
Site 118
Y857
H
R
R
N
S
R
A
Y
S
K
N
V
E
G
Q
Site 119
S858
R
R
N
S
R
A
Y
S
K
N
V
E
G
Q
D
Site 120
Y871
Q
D
L
L
L
K
E
Y
P
N
N
F
S
S
S
Site 121
S878
Y
P
N
N
F
S
S
S
Q
Q
C
A
A
A
S
Site 122
S885
S
Q
Q
C
A
A
A
S
P
P
G
L
P
S
E
Site 123
S891
A
S
P
P
G
L
P
S
E
N
Q
D
L
C
A
Site 124
Y899
E
N
Q
D
L
C
A
Y
G
L
P
S
L
N
Q
Site 125
S903
L
C
A
Y
G
L
P
S
L
N
Q
S
Q
E
T
Site 126
S907
G
L
P
S
L
N
Q
S
Q
E
T
K
S
L
W
Site 127
S912
N
Q
S
Q
E
T
K
S
L
W
W
E
R
R
A
Site 128
S943
K
K
D
Q
V
E
R
S
S
T
A
F
H
G
E
Site 129
S944
K
D
Q
V
E
R
S
S
T
A
F
H
G
E
I
Site 130
T945
D
Q
V
E
R
S
S
T
A
F
H
G
E
I
F
Site 131
T954
F
H
G
E
I
F
G
T
S
V
P
E
N
G
H
Site 132
S955
H
G
E
I
F
G
T
S
V
P
E
N
G
H
H
Site 133
S967
G
H
H
P
K
K
Q
S
D
G
M
E
E
Y
K
Site 134
Y973
Q
S
D
G
M
E
E
Y
K
T
F
G
L
G
L
Site 135
T975
D
G
M
E
E
Y
K
T
F
G
L
G
L
T
N
Site 136
T981
K
T
F
G
L
G
L
T
N
V
K
K
N
R
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation