PhosphoNET

           
Protein Info 
   
Short Name:  SLC12A8
Full Name:  Solute carrier family 12 member 8
Alias:  Cation-chloride cotransporter 9
Type: 
Mass (Da):  78223
Number AA:  714
UniProt ID:  A0AV02
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S103GERSSIGSGGVYSMI
Site 2S215EHGFIGYSPELLQNN
Site 3T223PELLQNNTLPDYSPG
Site 4Y227QNNTLPDYSPGESFF
Site 5S228NNTLPDYSPGESFFT
Site 6S263DLREPAASIPPGSLA
Site 7Y297CTREALRYDFLIAEK
Site 8T359QGKGPNKTPVAAICL
Site 9S430GAEGLHCSEHLLLEK
Site 10S440LLLEKAPSYGSEGPA
Site 11Y441LLEKAPSYGSEGPAQ
Site 12T454AQRVLEGTLLEFTKD
Site 13S475LTRKLESSQPRQGEG
Site 14T485RQGEGNRTPESQKRK
Site 15S488EGNRTPESQKRKSKK
Site 16S493PESQKRKSKKATKQT
Site 17T500SKKATKQTLQDSFLL
Site 18S504TKQTLQDSFLLDLKS
Site 19S514LDLKSPPSFPVEISD
Site 20S520PSFPVEISDRLPAAS
Site 21S527SDRLPAASWEGQESC
Site 22S542WNKQTSKSEGTQPEG
Site 23S563VPELCNQSESSGEDF
Site 24S574GEDFFLKSRLQEQDV
Site 25S635YFYIGRASPGLHLGS
Site 26S644GLHLGSASNFSFFRW
Site 27S647LGSASNFSFFRWMRS
Site 28S659MRSLLLPSCRSLRSP
Site 29S662LLLPSCRSLRSPQEQ
Site 30S665PSCRSLRSPQEQIIL
Site 31Y699DFATRDRYHHSSLVN
Site 32S703RDRYHHSSLVNREQL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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